Curcumol reduces lower limb arteriosclerosis in rats by inhibiting human arterial smooth muscle cell activity
Shengzhuang Yang,
Gaosheng Huang,
Xiangsen Liang
et al.
Abstract:Cardiovascular diseases, particularly those involving arterial stenosis and smooth muscle cell proliferation, pose significant health risks. This study aimed to investigate the therapeutic potential of curcumol in inhibiting platelet‐derived growth factor‐BB (PDGF‐BB)‐induced human aortic smooth muscle cell (HASMC) proliferation, migration and autophagy. Using cell viability assays, 5‐ethynyl‐2′‐deoxyuridine (EdU) incorporation assays and Western Blot analyses, we observed that curcumol effectively attenuated … Show more
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