“…It has been considered as a potent antioxidative molecule, capable of neutralizing FRs and inhibiting OS cascade (Jayaprakasha et al, 2006). It has been reported that incorporating CUR in the diet of ruminants can help with a variety of issues, including reducing subclinical mastitis in dairy sheep (Jaguezeski et al, 2018), modulating fatty acid profile in lamb meat (Marcon et al, 2020) and serum inflammatory, antioxidant and immune response in weaned calves (Molosse et al, 2022), reducing heat stress in rams (Jiang et al, 2019) and enhancing testicular blood flow and semen quality outside the breeding season in goats (El‐Sherbiny, Fathi, et al, 2022). The CUR and its nanoform have been reported to induce vasorelaxation of goat's middle uterine artery (MUA) in vitro, through different mechanisms, such as sodium‐potassium (Na + ‐K + ) ATPase augmentation (Parija et al, 2021), aminoguanidine‐sensitive inducible NO synthase activation (Jandhyam & Parija, 2018b), potassium (K + ) channels opening (Jandhyam & Parija, 2018a), transient potential vanilloid receptor 1 sensitization (Parija & Jandhyam, 2018) and endothelial‐based stimulation of NO, prostaglandin I 2 and soluble guanylyl cyclase (Jandhyam & Parija, 2019).…”