Curcumin-loaded electrospun nonwoven as a colorimetric indicator for volatile amines

Luo, Xiaoyu; Lim, Loong‐Tak

doi:10.1016/j.lwt.2020.109493

Cited by 56 publications

(40 citation statements)

References 58 publications

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“…The broad absorption at 3435.1 cm − 1 has contributions from N-H bending vibrations. A same IR spectra for CUR and PVP was observed in a CUR-loaded PVP nano ber38 . Baganiz et alreported the same IR spectra for PVP in carboxylated PVP conjugated with interleukin-10 39 .…”

supporting

confidence: 66%

Characterization of PVPK90 core shell nanofibers containing curcumin prepared by emulsion electrospinning process

Kamali

Farzadnia

Movaffagh

et al. 2021

Preprint

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The pharmacological effects of curcumin (CUR) as a polyphenolic ingredient of turmeric affected by its water insolubility, poor bioavailability, and instability. The electrospun nanofibers of hydrophilic biodegradable polymer can be addressed this issue. The current study aimed to investigate the CUR-loaded core-shell PVPK90 nanofibers generated from O/W nanoemulsions. CUR-loaded PVPK90 fibers were prepared based on the central composite design and different levels of drug concentration, flow rate, amount of acetone, and organic phase percentage by electrospinning technique and their diameter and uniformity, tensile strength, wetting and disintegration time were evaluated. Then, DSC, FTIR, XRD, TEM, fluorescence microscopy, and drug release test were carried out on the optimized nanofibers. The formulation containing 6 mg/mL CUR, 30% organic phase, 0.4 mL acetone, and flow rate of 1 mL/h was selected as optimum formulation. The results were confirmed the core-shell bead-free uniform fibers at the nanometer scale. The optimum nanofiber showed a good flexibility, short wetting and disintegrating times as well as the amorphous structure. The drug release pattern indicated the rapid release of the drug within 30 min. Our findings confirm that the O/W emulsion electrospinning-based PVPK90 core-shell nanofiber would be beneficial as a novel delivery system for water insoluble drug.

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supporting

confidence: 66%

Characterization of PVPK90 core shell nanofibers containing curcumin prepared by emulsion electrospinning process

Kamali

Farzadnia

Movaffagh

et al. 2021

Preprint

View full text Add to dashboard Cite

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“…In contrast, printing techniques employed by the packaging industry, such as inkjet and laser printings, allow rapid transfer of indicator inks based on predesigned graphics with high print precision and accuracy (Liana et al., 2012; Nery & Kubota, 2013). These printing techniques allow prompt development of different indicator patterns with a large degree of freedom when it comes to multiplexing multiple dyes on the same print area (Luo et al., 2021; Luo & Lim, 2020b). Depending on the printing modes (e.g., thermal versus piezoelectric), equipment, and print substrate, the indicator solutions will have to be formulated and optimized for reliable printing practices.…”

Section: Indicator Preparation Methodsmentioning

confidence: 99%

“…As the solution is being electrified, multiple polymer jets are formed and ejected toward the collector to form the nonwovens. Curcumin‐laiden electrospun polyvinylpyrrolidone nonwovens, generated by using a free‐surface electrospinning, showed excellent sensitivity for the discrimination of different volatile amines such as trimethylamine, dimethylamine, and triethylamine (Luo & Lim, 2020a).…”

Section: Indicator Preparation Methodsmentioning

confidence: 99%

“…Natural lipophilic curcuminoids extracted from turmeric roots are well known for their bioactive and therapeutic effects, which have been generally attributed to their antioxidant and anti‐inflammatory properties (Hewlings & Kalman, 2017; Stanić, 2017). These yellow‐orange colorants can be used as indicators for alkaline analytes, where they change to red color due to the keto–enol transformation of their dicarbonyl structure, as shown in Figure 1 (Luo & Lim, 2020a; Stanić, 2017). This suggests its usage as a colorimetric indicator mainly in the pH range of 8−13.…”

Section: Types Of Indicatorsmentioning

confidence: 99%

“…This suggests its usage as a colorimetric indicator mainly in the pH range of 8−13. The highly conjugated configuration of curcuminoids also results in their fluorescence emission in green color, making them a promising fluorescent indicator (Luo & Lim, 2020a; Stanić, 2017). In addition, the color changes of curcuminoids can be triggered by the complexation with metal ions such as copper, iron, and lead (Raj & Shankaran, 2016; Saithongdee et al., 2014; Xu et al., 2016).…”

Section: Types Of Indicatorsmentioning

confidence: 99%

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A review on colorimetric indicators for monitoring product freshness in intelligent food packaging: Indicator dyes, preparation methods, and applications

Luo

Zaitoon

Lim

2022

Comp Rev Food Sci Food Safe

Self Cite

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Intelligent food packaging system exhibits enhanced communication function by providing dynamic product information to various stakeholders (e.g., consumers, retailers, distributors) in the supply chain. One example of intelligent packaging involves the use of colorimetric indicators, which when subjected to external stimuli (e.g., moisture, gas/vapor, electromagnetic radiation, temperature), display discernable color changes that can be correlated with real‐time changes in product quality. This type of interactive packaging system allows continuous monitoring of product freshness during transportation, distribution, storage, and marketing phases. This review summarizes the colorimetric indicator technologies for intelligent packaging systems, emphasizing on the types of indicator dyes, preparation methods, applications in different food products, and future considerations. Both food and nonfood indicator materials integrated into various carriers (e.g., paper‐based substrates, polymer films, electrospun fibers, and nanoparticles) with material properties optimized for specific applications are discussed, targeting perishable products, such as fresh meat and fishery products. Colorimetric indicators can supplement the traditional “Best Before” date label by providing real‐time product quality information to the consumers and retailers, thereby not only ensuring product safety, but also promising in reducing food waste. Successful scale‐up of these intelligent packaging technologies to the industrial level must consider issues related to regulatory approval, consumer acceptance, cost‐effectiveness, and product compatibility.

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Curcumin-loaded electrospun nonwoven as a colorimetric indicator for volatile amines

Cited by 56 publications

References 58 publications

Characterization of PVPK90 core shell nanofibers containing curcumin prepared by emulsion electrospinning process

Characterization of PVPK90 core shell nanofibers containing curcumin prepared by emulsion electrospinning process

A review on colorimetric indicators for monitoring product freshness in intelligent food packaging: Indicator dyes, preparation methods, and applications

Natural Antioxidants from Fruit By-products for Active Packaging Applications

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