Cumulative incidence and risk factors for medication-related osteonecrosis of the jaw during long-term prostate cancer management
Masaru Tani,
Koji Hatano,
Akihiro Yoshimura
et al.
Abstract:Bone-modifying agents (BMA) are extensively used in treating patients with prostate cancer with bone metastases. However, this increases the risk of medication-related osteonecrosis of the jaw (MRONJ). The safety of long-term BMA administration in clinical practice remains unclear. We aimed to determine the cumulative incidence and risk factors of MRONJ. One hundred and seventy-nine patients with prostate cancer with bone metastases treated with BMA at our institution since 2008 were included in this study. Tw… Show more
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