Culture proven Salmonella typhi co-infection in a child with Dengue fever: a case report

Srinivasaraghavan, Rangan; Parameswaran, Narayanan; Kanimozhi, Thandapani

doi:10.3855/jidc.5230

Cited by 17 publications

(17 citation statements)

References 12 publications

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“…4 Srinivasaraghavan et al in their case utilized NS1 antigen and IgM antibody for dengue fever and Widal test and blood culture for enteric fever. 5 Previously, Sudjana and Jusuf reported similar coinfections from Indonesia. 22 Sharma et al conducted a study to find out the coinfection rates in North Delhi; of the 141 serologically-diagnosed dengue cases, 11 were coinfected with enteric fever, evidenced by positive Widal test, so, the coinfection rate was 7.8%.…”

Section: Discussionmentioning

confidence: 94%

“…Actually, a few cases of such dengue-enteric fever coinfection have been reported so far, mostly from India. [1][2][3][4][5] Given that both dengue and enteric fever are endemic in Bangladesh, coinfection involving them is likely here as well, though to the best of our knowledge, none have yet been reported. On the other hand, high degree of suspicion is needed to think of the probability of dengue-enteric fever coinfection in individual patient, though uncommon, otherwise grave consequences may result.…”

Section: Introductionmentioning

confidence: 99%

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Dengue coinfection in a case of enteric fever: a diagnostic and therapeutic dilemma

Islam

Islam²,

Jesmin³

2018

Bangla J Med

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Section: Discussionmentioning

confidence: 94%

Section: Introductionmentioning

confidence: 99%

Dengue coinfection in a case of enteric fever: a diagnostic and therapeutic dilemma

Islam

Islam²,

Jesmin³

2018

Bangla J Med

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“…The knowledge is still poor regarding arboviral febrile infection, because the clinical guidelines on management of febrile patient in low resource areas focus only on bacterial and malarial infection (19). Moreover there is lack of awareness among clinicians on concurrent of infection due to multiple agents (20). Non speci c clinical presentation, limited diagnostic capacities and weak surveillance system made the burden grow big and unnoticed (13).…”

Section: Discussionmentioning

confidence: 99%

Chikungunya and dengue virus infection among febrile children in North-Eastern Tanzania: prospective study

Saro¹,

Kajeguka²,

Azizi³

et al. 2020

Preprint

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Background There are several unknown illnesses including chikungunya and dengue viruses that present with fever in children. Therefore there are many cases that are misdiagnosed. Consequently we performed a study to determine the clinical characteristics of dengue and chikungunya in order to assist clinicians in management. Methods A total of 196 children with history of fever for ≤ 10 days were enrolled prospectively at Kilimanjaro Christian Medical Centre from September 2015 to May 2016. All cases were screened for chikungunya and dengue viruses by PCR as well as other febrile illnesses such as malaria, bacteria and HIV through other diagnostic method. We performed logistic regression to find association between clinical symptoms and chikungunya infection. Results In our study, 21.9% (43/196) of the cases received laboratory investigations and the diagnoses were as follows; malaria only (n = 1, 0.5%), bacterial infections only (n = 4, 2.0%), HIV/AIDS only (n = 37, 18.9%), as well as malaria, meningitis and urinary tract co-infection (n = 1, 0.5%). Further investigation of all cases revealed that 11.7%( 23) had chikungunya virus while none had dengue virus. For the cases of chikungunya, 78.3% (18) were below 5 years of age, 65.2%( 15) were females, majority were from Kilimanjaro 95.7%( 22) and Arusha region 4.3% (1). The clinical features were as follows; nausea/vomit 50.0% (98), cough 48.5% (95), convulsion/comma 34.7%( 68), diarrhea 26.0% (51), joint pain 13.3% (26), sore throat 7.1%( 14), rashes 4.1%(8)chills 2.6%༈5༉. Nevertheless, there was no statistical significant relationship between chikungunya virus and aforementioned symptoms/signs according to logistic regression. Conclusion This study reveals that chikungunya infection is common cause of febrile illnesses; however it does not have treatment. Therefore, we encourage chikungunya infection to be included in routine investigation as these children are receiving inappropriate treatments such as antibiotics and ant malarial which should be avoided in order to minimize over use of drugs and resource wastage.

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“…It is highly probable that these might not be true co-infections but only serological cross-reactivity. However, true co-infection have been reported [13,14].…”

Section: Discussionmentioning

confidence: 99%

Aetiology and clinical spectrum of acute undifferentiated febrile illness in hospitalized children

Prabha

Chandrasegaran

et al. 2017

Int J Pediatr Res

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Introduction:Acute fever of 2 weeks duration with non-specific signs and symptoms is known as acute undifferentiated febrile illness (AUFI). Owing to non-specific presentation, it remains a diagnostic challenge. Hence the present study focuses on etiology and clinical profile of undifferentiated febrile illness. Methodology: All children aged 2-12 years admitted with fever of 5-15 days duration, for which no cause was found after a thorough history and clinical examination were included from July 2015 to June 2016 prospectively. History, examination findings, investigations and the treatment details were recorded. Data analyzed using SSPS software. Results: Total sample size was 263. The mean age was 6.7 ± 3.4 years. Most common symptoms were cough and vomiting. The most common diagnosis arrived at was Scrub typhus (22.4%) followed by Dengue (11%), Enteric fever (11%), Co-infections (6.1%), Urinary tract infections (3%) and Lower respiratory tract infections (2.3%). Fever was still undiagnosed in 116 children (44.1%). No malarial infection was noted. Conclusion: Non-malarial infections are common in this part of the country in children with AUFI.

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Culture proven Salmonella typhi co-infection in a child with Dengue fever: a case report

Cited by 17 publications

References 12 publications

Dengue coinfection in a case of enteric fever: a diagnostic and therapeutic dilemma

Dengue coinfection in a case of enteric fever: a diagnostic and therapeutic dilemma

Chikungunya and dengue virus infection among febrile children in North-Eastern Tanzania: prospective study

Aetiology and clinical spectrum of acute undifferentiated febrile illness in hospitalized children

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