Cultural development and psychopathology

Causadías, José M.; Cicchetti, Dante

doi:10.1017/s0954579418001220

Cited by 39 publications

(36 citation statements)

References 63 publications

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“…The current study leverages the results of the most extensive genetic discovery efforts to date on depression, to investigate whether (a) depression PRS are associated with lifetime and past year MDD diagnosis or MDE, and (b) adversity moderates the relationship between depression genetic liability and MDD or MDE in a sample of Mexican adolescents. This work is consistent with a recent call for work to consider the joint contributions of context and biology among ethnic minority populations (Causadias and Cicchetti, 2018).…”

Section: Introductionsupporting

confidence: 91%

Depression polygenic scores are associated with major depressive disorder diagnosis and depressive episode in Mexican adolescents

Rabinowitz

Campos

Benjet

et al. 2020

Preprint

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Objective. Large-scale genome-wide association studies have uncovered genetic variants associated with depression; however, most of this work has been limited to adults of European ancestry. We investigate the ability of depression polygenic risk scores (PRS) to predict both lifetime and past year major depressive disorder (MDD) diagnosis and the experience of a major depressive episode (MDE) in a sample of adolescents with admixed ancestry from Mexico City, and explore whether adverse life events moderate these relations. Methods. The study sample consisted of adolescents (N=1,152) aged 12-17 from Mexico City who were interviewed and genotyped as part of a general population survey on adolescent mental health. PRS for depression were derived using summary statistics from a large-scale discovery genome-wide association study (GWAS) conducted on depressive symptoms that included over 800,000 individuals of European ancestry (Howard et al., 2019). Results. Higher depression PRS were associated with a higher likelihood of both past year MDD and MDE and lifetime MDE, accounting for 1.5%-2.5% of the variance in these outcomes. Adversity did not moderate the relationship between depression PRS and lifetime or past year MDD or MDE. Limitations. This study is cross-sectional. As such, a few participants might have experience MDD/MDE after the interview. In addition, our sample comprised only Mexican youth and thus it may not generalize to other populations. Conclusions. Our results indicate that depression PRS derived from a European ancestry GWAS are associated with MDD and MDE risk among Mexican adolescents and have the potential to aid in the identification of youth who may be genetically prone to developing depressive symptoms.

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Section: Introductionsupporting

confidence: 91%

Depression polygenic scores are associated with major depressive disorder diagnosis and depressive episode in Mexican adolescents

Rabinowitz

Campos

Benjet

et al. 2020

Preprint

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“…Cultural promotive factors are those processes that enhance the likelihood of initiating and maintaining trajectories of positive outcomes related to adaptation and well-being (Gaylord-Harden et al, 2018). In contrast, cultural risk factors are those processes that heighten the probability of initiating or maintaining trajectories of psychopathology and negative health (Causadias & Cicchetti, 2018), including behavioral and emotional problems (García Coll et al, 1996). Cultural protective factors are those processes that reduce the likelihood of developing maladaptive outcomes in the context of risk (e.g., poverty, community violence or danger); as such, protective factors are typically evidenced by an interaction between a source of risk and familism values leading to a reduction in maladaptive outcomes (Causadias & Cicchetti, 2018; Neblett et al, 2012).…”

Section: Familism and Adjustment/relationship Qualitymentioning

confidence: 99%

Familism values and adjustment among Hispanic/Latino individuals: A systematic review and meta-analysis.

Cahill¹,

Updegraff²,

Causadías³

et al. 2021

Psychological Bulletin

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Familism is a key cultural value that emphasizes support and attachment, loyalty, honor, and obligation to the family and is hypothesized to be critical in shaping family dynamics and individual adjustment among Hispanic/Latino individuals. To advance the field, we drew from cultural-ecological and developmental models to examine familism as a cultural promotive and risk factor for individual adjustment and family relationship quality. We conducted a systematic review and meta-analysis via a search between 2017 and 2020 and identified 126 records (23% unpublished dissertations) from 73 independent studies (12% longitudinal) in PsycINFO/Proquest, PubMed, and ERIC databases between 1993 and 2019. The multilevel meta-analysis revealed significant effects: educational outcomes, r = .16, 95% CI [.08, .23]; family relationships, which included warmth/support, r = .24, 95% CI [.19, .29], and conflict/negativity, r = −.13, 95% CI [−.23, −.02]; internalizing symptoms, r = −.12, 95% CI [−.16, −.09]; and externalizing symptoms, r = −.10, 95% CI [−.18, −.03]. We tested conceptually driven moderators and found significant variation by sample (e.g., nativity, developmental period) and context characteristics (i.e., U.S. states characterized as “established” or “new/emerging” for Hispanic/Latino populations). Findings suggest that familism may function more as a promotive and less as a risk factor and that continued attention is needed to the conditions that strengthen or weaken these associations. Although conclusions are limited because most effect sizes were from cross-sectional designs with U.S. Mexican-origin participants and relied on self-reports, findings highlight the complex associations between familism and adjustment/relationship quality and can guide future research.

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“…The few FSM studies examining Latino children have focused primarily on middle childhood and adolescence and provide evidence for the mediating role of maternal depression between poverty-related stressors and socioemotional child outcomes [29,30] as well as revealing culture-specific ways in which these variables may interact [31,32]. However, not only do we know little about the validity of these models for Latino children during early childhood [33] but culture-specific stressors have rarely been used as anchors for these studies-despite the integral role of cultural influences on developmental processes [34,35].…”

Section: Plos Onementioning

confidence: 99%

Maternal depression in Latinas and child socioemotional development: A systematic review

Harris

Santos

2020

PLoS ONE

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Background Although substantial research exists on the debilitating effects of maternal depression on child development, little is known about Latina mothers with depression and their young children within the broader context of sociocultural and economic stressors. Objectives What is the relationship between maternal depression in Latina mothers and their children's socioemotional outcomes through early developmental windows (0-5 years)? Methods We searched electronic databases PubMed, CINAHL, and PsycINFO in this systematic review, pre-registered via PROSPERO (CRD42019128686). Based on predetermined criteria, we identified 56 studies and included 15 in the final sample. After extracting data, we assessed study quality with the National Heart, Lung, and Blood Institute Quality Assessment Tool for Observational Cohort and Cross-Sectional Studies. Results We found inverse correlations between maternal depression and child socioemotional outcomes; furthermore, we found evidence of a moderating and mediating role of maternal depression between contextual stressors and child outcomes. Children of U.S.-born Latina mothers had poorer developmental outcomes than children of foreign-born Latina mothers across socioemotional domains and throughout early developmental windows. Conclusions Future research must examine underlying mechanisms for the potential Latino paradox in young Latino children's socioemotional outcomes. Policies should support mental health of Latina mothers as early as the prenatal period.

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Cultural development and psychopathology

Cited by 39 publications

References 63 publications

Depression polygenic scores are associated with major depressive disorder diagnosis and depressive episode in Mexican adolescents

Depression polygenic scores are associated with major depressive disorder diagnosis and depressive episode in Mexican adolescents

Familism values and adjustment among Hispanic/Latino individuals: A systematic review and meta-analysis.

Maternal depression in Latinas and child socioemotional development: A systematic review

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