Cultural Adaptation of a Compliance Questionnaire for Patients with Rheumatoid Arthritis to a Korean Version

Abstract

Background/AimsThe Compliance Questionnaire-Rheumatology (CQR) is a validated scale to evaluate patient compliance for anti-rheumatic medications. We developed a Korean version of the CQR (KCQR) and confirmed its reliability and validity.MethodsWe prepared the KCQR by translating and back-translating the original CQR with modifications to adapt it to Korean culture. Fifty Korean patients with rheumatoid arthritis (RA) were enrolled in this study. The test-retest reliability of the KCQR was evaluated at a 2-week interval using the intraclass correlation coefficient (ICC). The validity of the KCQR was assessed by identifying associations between KCQR scores and patient compliance, measured using pharmacy refill data.ResultsThe reliability of the KCQR was adequate, with an ICC of 0.71 for test-retest reliability. With respect to validity, the summed score of the weighted KCQR showed a significant correlation with pharmacy refill data (r2 = 0.57) on multiple regression analysis.ConclusionsOur results indicate that the KCQR is a reliable, valid instrument to evaluate compliance of Korean patients for RA medications.

Cross-Cultural Adaptation, Reliability, and Validity of the Turkish Version of the Compliance Questionnaire on Rheumatology in Patients With Behçet’s Disease

“…These results demonstrated the repeatability and test–retest reliability of the scale. Several validation studies focused on different languages for this scale have been conducted (de Klerk et al, 2003; Lee et al, 2011). Lee et al (2011) validated the Korean version of this scale in patients with rheumatoid arthritis, and the intraclass correlation coefficient was .71.…”

“…Several validation studies focused on different languages for this scale have been conducted (de Klerk et al, 2003; Lee et al, 2011). Lee et al (2011) validated the Korean version of this scale in patients with rheumatoid arthritis, and the intraclass correlation coefficient was .71. De Klerk et al (2003) validated it in patients with rheumatoid arthritis, polymyalgia, and gout, where it was compared to an electronic medication monitoring system, showing a sensitivity and specificity of 98% and 67% to detect good adherence to treatment.…”

“…Since there are various effective treatment alternatives, the chance of success will be highest with the patient’s compliance to therapy. The importance of this issue in various chronic disorders has been studied, and it has been reported that better clinical outcomes are directly associated with better compliance (Lee et al, 2011; Nuesch, Schroeder, Dieterle, Martina, &Battegay, 2001). Correspondingly, noncompliance has been found to be associated with unnecessary health costs, changes in treatment, morbidity, and even mortality (Osterberg &Blaschke, 2005).…”

“…Theoretically, direct methods such as measuring blood levels or metabolites for the presence of the prescribed drugs in serum or urine can reliably determine compliance. Nevertheless, in clinical practice this method is expensive, invasive, and time-consuming; furthermore, a number of factors such as drug interactions and physiological differences can affect the results (Arturi et al, 2013; Lee et al, 2011; Yang et al, 2014). For these reasons, indirect methods including pill counts, medication-event monitoring systems, and self-reporting questionnaires have attracted attention and are widely studied (Modi, Zeller, Xanthakos, Jenkins, &Inge, 2013; Yang et al, 2014).…”

Contribution of Personality Traits, Psychological Factors, and Health-Related Quality of Life to Medication Adherence in Patients with Rheumatoid Arthritis

“…3 The CQR has been translated, and back-translation of the original CQR with modification for use in Koreans revealed that this measure has good reliability in RA patients. 22 Personality traits were assessed with the validated Korean version of the 10-item short version of the Big Five Inventory-10 (K-BFI-10). The BFI-10 is a short-form of the Big Five Personality Inventory that consists of two items for each of the five personality traits, namely extraversion, agreeableness, conscientiousness, neuroticism, and openness to experience.…”