Cuestionario de detección de deterioro cognitivo AD8-arg para su uso Atención Primaria de la salud en Argentina

Blanco, Romina; Román, Fabian; Iturry, Mónica; Leis, Adriana; Russo, María Julieta; Bartoloni, Leonardo; Barceló, Ernesto; Allegri, Ricardo

doi:10.1016/j.neuarg.2016.10.001

Cited by 4 publications

(2 citation statements)

References 18 publications

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“…40 Researchers have observed higher levels of sensitivity when validating the AD8 with Latin American samples. Carnero-Pardo and colleagues’ 41 large Spanish study (n = 401) yielded 93% sensitivity and 81% specificity cognitive impairment with a cutoff score of 3/4, while Blanco et al, 95 working with a notably smaller Argentinian sample (n = 62), found that a cutoff score of 2 best balanced sensitivity and specificity at 80% and 83% when detecting dementia, and noted minor differences in translation choices from the Spanish study. Specificity detecting MCI was considerably lower at 44%.…”

Section: Informant Report Measuresmentioning

confidence: 96%

The Utility of Cognitive Screeners in the Detection of Dementia Spectrum Disorders in Spanish-Speaking Populations

Burke

Grudzien

Burgess

et al. 2020

J Geriatr Psychiatry Neurol

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Increasing rates of dementia spectrum disorders among Spanish-speaking geriatric populations necessitate the development of culturally appropriate cognitive screening tests that can identify neurodegenerative disorders in their earliest stages when emerging disease-modifying treatments are most likely to be effective. This scoping review identified 26 brief Spanish language cognitive screening tools (<20 minutes) by searching academic databases using a combination of search terms. Results suggest that the Mini-Mental Status Examination and Montreal Cognitive Assessment appear to be less valid than other screeners. Instruments such as the 7-Minute Screen and Mini-Cog evidence higher classification rates of dementia, while Phototest detected mild cognitive impairment at higher rates more consistently than other screeners. Different sensitivity and specificity outcomes and cutoffs were observed when the same cognitive screener was evaluated in different countries. Results indicate that it is imperative to increase nation-specific validation and normative data for these instruments to best serve diverse populations.

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Section: Informant Report Measuresmentioning

confidence: 96%

The Utility of Cognitive Screeners in the Detection of Dementia Spectrum Disorders in Spanish-Speaking Populations

Burke

Grudzien

Burgess

et al. 2020

J Geriatr Psychiatry Neurol

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“…It is made up of eight items that allow an informant to assess whether there have been changes in the functional aspects consulted. It is sensitive to CI and has been validated in Latin American populations 27 …”

Section: Methodsmentioning

confidence: 99%

Factors associated with cognitive impairment in Latin American older adults: A cross‐sectional observational study of COVID‐19 confinement

Ramos‐Henderson

Soto‐Añari²,

Herrera‐Pino

et al. 2023

Alz & Dem Diag Ass & Dis Mo

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INTRODUCTION The effects of COVID‐19 confinement have been severe, especially in older adults. Therefore, we analyzed the factors associated with cognitive impairment (CI) in Latin America (LA). METHODS We conducted a cross‐sectional observational study with a total of 5245 older adults from 10 countries in LA. Measurement We used the Telephone Montreal Cognitive Assessment (T‐MoCA) and the Eight‐item Informant Interview to Differentiate Aging and Dementia (AD8) scale. RESULTS We found that age, depressive symptomatology, bone fractures, being widowed, having a family member with dementia, and unemployment were associated with an increased risk of CI. In contrast, higher education, hypertension with continuous treatment, quarantine, and keeping stimulating cognitive and physical activities were associated with a lower probability of CI. No significant association was found between suffering from diabetes or being retired and CI. DISCUSSION It is essential to conduct follow‐up studies on these factors, considering their relationship with CI and the duration of confinement.

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AD-8 for detection of dementia across a variety of healthcare settings

Hendry

Green

McShane

et al. 2019

Cochrane Database of Systematic Reviews

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A B S T R A C T BackgroundDementia assessment often involves initial screening, using a brief tool, followed by more detailed assessment where required. The AD-8 is a short questionnaire, completed by a suitable 'informant' who knows the person well. AD-8 is designed to assess change in functional performance secondary to cognitive change. ObjectivesTo determine the diagnostic accuracy of the informant-based AD-8 questionnaire, in detection of all-cause (undifferentiated) dementia in adults. Where data were available, we described the following: the diagnostic accuracy of the AD-8 at various predefined threshold scores; the diagnostic accuracy of the AD-8 for each healthcare setting and the effects of heterogeneity on the reported diagnostic accuracy of the AD-8. CINAHL (EBSCOhost) and LILACS (BIREME). We checked reference lists of relevant studies and reviews, used searches of known relevant studies in PubMed to track related articles, and contacted research groups conducting work on the AD-8 to try to find additional studies. We developed a sensitive search strategy and used standardised database subject headings as appropriate. Foreign language publications were translated. Selection criteriaWe selected those studies which included the AD-8 to assess for the presence of dementia and where dementia diagnosis was confirmed with clinical assessment. We only included those studies where the AD-8 was used as an informant assessment. We made no exclusions in relation to healthcare setting, language of AD-8 or the AD-8 score used to define a 'test positive' case. AD-8 for detection of dementia across a variety of healthcare settings (Review) Data collection and analysisWe screened all titles generated by electronic database searches, and reviewed abstracts of potentially relevant studies. Two independent assessors checked full papers for eligibility and extracted data. We extracted data into two-by-two tables to allow calculation of accuracy metrics for individual studies. We then created summary estimates of sensitivity, specificity and likelihood ratios using the bivariate approach and plotting results in receiver operating characteristic (ROC) space. We determined quality assessment (risk of bias and applicability) using the QUADAS-2 tool. Main resultsFrom 36 papers describing AD-8 test accuracy, we included 10 papers. We utilised data from nine papers with 4045 individuals, 1107 of whom (27%) had a clinical diagnosis of dementia. Pooled analysis of seven studies, using an AD-8 informant cut-off score of two, indicated that sensitivity was 0.92 (95% confidence interval (CI) 0.86 to 0.96); specificity was 0.64 (95% CI 0.39 to 0.82); the positive likelihood ratio was 2.53 (95% CI 1.38 to 4.64); and the negative likelihood ratio was 0.12 (95% CI 0.07 to 0.21). Pooled analysis of five studies, using an AD-8 informant cut-off score of three, indicated that sensitivity was 0.91 (95% CI 0.80 to 0.96); specificity was 0.76 (95% CI 0.57 to 0.89); the positive likelihood ratio was 3.86 (95% CI 2.03 to 7.34); and the negativ...

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Cuestionario de detección de deterioro cognitivo AD8-arg para su uso Atención Primaria de la salud en Argentina

Cited by 4 publications

References 18 publications

The Utility of Cognitive Screeners in the Detection of Dementia Spectrum Disorders in Spanish-Speaking Populations

The Utility of Cognitive Screeners in the Detection of Dementia Spectrum Disorders in Spanish-Speaking Populations

Factors associated with cognitive impairment in Latin American older adults: A cross‐sectional observational study of COVID‐19 confinement

AD-8 for detection of dementia across a variety of healthcare settings

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