Cucurbituril

Molecular recognition of organic ammonium ions in solution using synthetic receptors

“…Alkylammonium ions were the first organic guests to be reported for CB[6] ( 131a ) [ 406 ]. Mock [ 407 ], Buschmann and co-workers [ 408 – 409 ], and Kim et al [ 410 ] further investigated the molecular-recognition properties. Cucurbiturils bind their guests by hydrogen-bonding or ion-dipole interactions in combination with the hydrophobic effect of the cavity.…”

Cucurbit[n]uril Derivatives Soluble in Water and Organic Solvents

“…The 1 H and 13 C NMR spectra reveal that the mixture contains cyclic pentamer (n 5) and hexamer (n 6) as major products (in a $ 8:1 ratio), and a small amount of unidentified homologues. After a series of dissolution and fractional crystallizations, the pentamer (CB* [5]) and hexamer (CB* [6]) were isolated from the mixture in 16 % and 2 % yields, respectively.…”

“…We may also be able to synthesize other homologues containing higher numbers of substituted glycoluril units. During the past few decades the design and high-yielding syntheses of interlocked macrocyclic molecules, the catenanes, [1] have evolved mainly as a result of the elegant and inspirational transition metal and organic templated synthetic (5.0 mL) were added, the purple solution was heated at 80 8C for 24 h. The solution was allowed to cool to room temperature, and then diluted with water (10 mL). The solution was poured into acetone (300 mL) to precipitate a solid, which was collected by filtration, and redissolved in water (50 mL).…”

“…Recrystallization of the crude products from water produced colorless crystalline products CB* [5] (356.7 mg, 16 %) and CB* [6] (47.8 mg, 2 %). CB* [5]: 1 …”

Novel supramolecular compounds based on Cucurbit[6]uril, 1,8-diaminooctane and octahedral thiohydroxo anions with cluster core [Re6S8]

“…The van-der-Waals diameter of the inner cavity is about 5.5 Å [1]. Due to the large size of the cavity, Cuc[6] is capable of holding small organic molecules [2][3][4][5].…”