CuBr₂-mediated dehydrogenative [4+2] annulation of 1-naphthyl-1,3-indandiones and alkenes

Abstract

Intermolecular annulation reactions of 1-naphthyl-1,3-indandiones with alkenes proceed efficiently in the presence of a copper catalyst to generate spirocarbocycle compounds. Various spirocyclic molecules bearing an all-carbon quaternary center could be...