CuBi2O4 Synthesis, Characterization, and Application in Sensitive Amperometric/Voltammetric Detection of Amoxicillin in Aqueous Solutions

Abstract

CuBi2O4 synthesized by thermolysis of a new Bi(III)-Cu(II) oxalate coordination compound, namely Bi2Cu(C2O4)4·0.25H2O, was tested through its integration within carbon nanofiber paste electrode, namely CuBi/carbon nanofiber (CNF), for the electrochemical detection of amoxicillin (AMX) in the aqueous solution. Thermal analysis and IR spectroscopy were used to characterize a CuBi2O4 precursor to optimize the synthesis conditions. The copper bismuth oxide obtained after a heating treatment of the precursor at 700 °C/1 h was investigated by an X-ray diffraction and scanning electron microscopy. The electrochemical behavior of CuBi/CNF in comparison with CNF paste electrode showed the electrocatalytic activity of CuBi2O4 toward amoxicillin detection. Two potential detections, with one at the potential value of +0.540 V/saturated calomel electrode (SCE) and the other at the potential value of −1.000 V/SCE, were identified by cyclic voltammetry, which were exploited to develop the enhanced voltammetric and/or amperometric detection protocols. Better electroanalytical performance for AMX detection was achieved for CuBi/CNF using differential-pulsed and square-wave voltammetries than others reported in the literature. Very nice results obtained through anodic and cathodic currents recorded at +0.750 V/SCE and −1.000 V/SCE in the same time period using a pseudo multiple-pulsed amperometry technique showed the great potential of the CuBi/CNF paste electrode for practical applications in amoxicillin detection in aqueous solutions.

Nanostructured material‐based optical and electrochemical detection of amoxicillin antibiotic

“…Similarly, Dumitru et al synthesized copper bismuth oxide (CuBi 2 O 4 ) and used it to detect AMX in food samples. [ 65 ] CuBi 2 O 4 was mixed with carbon nanofibres to increase the electrochemical detection efficiency for AMX.…”

“…The voltammetric response of original GCE and GCE modified with it to detect AMX in food samples. [65] CuBi 2 O 4 was mixed with carbon nanofibres to increase the electrochemical detection efficiency for AMX.…”

Electrochemical Method for Ease Determination of Sodium Diclofenac Trace Levels in Water Using Graphene—Multi-Walled Carbon Nanotubes Paste Electrode

“…When the main advantages of carbon paste electrode related to easily renewable and modified surface is taken into account, as well as its low cost, the obtaining of nanostructured carbon paste electrode is facile for its further modification in developing the electrochemical detection of DCF [ 28 , 37 , 38 , 39 ]. In fact, the paste composition of the electrode is very easily further modified by simple mixing of carbon with certain oils and modifying component without any template or matrix development.…”

Characterization and Applications of Metal Ferrite Nanocomposites

“…This Special Issue also includes the study of Dumitru et al [ 11 ] on Bi 2 Cu(C 2 O 4 ) 4 ·0.25H 2 O synthesis by thermolysis, followed by its integration within a CuBi/carbon nanofiber (CNF) paste electrode and its application in the electrochemical detection of amoxicillin (AMX) in aqueous solution. The obtained results indicated the potential use of a CuBi/CNF paste electrode for AMX detection in aqueous solutions.…”

“…The obtained results indicated the potential use of a CuBi/CNF paste electrode for AMX detection in aqueous solutions. By adding a concentration step into the detection protocol, the selective and simultaneous detection of AMX in a multi-component matrix is also possible [ 11 ].…”