Cu²⁺-BTC based metal–organic framework: a redox accessible and redox stable MOF for selective and sensitive electrochemical sensing of acetaminophen and dopamine

Abstract

A Cu2+ plus benzenetricarboxylate (BTC) based ‘3D’ metal–organic framework HKUST-1 was synthesized via a facile microwave assisted route.

Copper Based Organic Framework Modified Electrosensor for Selective and Sensitive Detection of Ciprofloxacin

“…Diffusion controlled kinetics was observed for Cu MOF modified ITO electrode [60]. Similar diffusion controlled behaviour of Cu MOF is also reported by Sofi et al [46]. Since we are monitoring Cu MOF signal for detection of CIP, repetitive CV scans of Cu MOF/GC in 0.1 M PBS (pH 8) at scan rate of 0.1 V/s were recorded to check stability of signal ( figure S2).…”

“…As particle is made up of many crystallites consequently the particle size will be larger than crystallite size [45]. Similar results are reported for Cu BTC MOF by Sofi et al [46].…”

“…The anodic peak (A1) in the CV recorded for Cu MOF/GC electrode at 0.024 V corresponds to one electron oxidation of Cu to Cu + and a hump (A2) at 0.15 V denotes further one electron oxidation of Cu + to Cu 2 + . Similarly, two reduction peaks in backward scan at À 0.22 V (C1) and À 0.094 V (C2) correspond to one electron reduction of Cu 2 + to Cu + and Cu + to Cu respectively [46]. The probable reaction mechanism as mentioned by Loera-Serna et al [56] is as follows: fCu 2þ Rg n þ zyCl À 1 ðsÞ þ ðn À zÞK þ ðsÞ þ eÀ ¼ fCu þ ðK þ ÞRg nÀ z þ zCuCly ðsÞ þ zR 2À…”

“…But copper MOF is reported as an electroactive MOF as the copper atoms in Cu BTC are present in Cu (II) oxidation state with partially occupied d-orbitals, which results in the metallic states at the Fermi level [55]. The electrochemical activity of Cu BTC MOF is studied by various researchers where it has been explored as a sensing platform for different analytes [34][35][36]46].…”

Chemically modified electrodes with MOFs for the determination of inorganic and organic analytesviavoltammetric techniques: a critical review

“…24,25 Recently, Li et al 22 and F.A. Sofi et al 26 described the development of a glassy carbon electrode modified with HKUST-1 as a sensitive electrochemical sensor for the determination of dopamine, an important neurotransmitter in the mammalian central nervous system, using Differential Pulse Voltammetry (DPV). They managed to detect the targeted analyte in a wide range of concentrations ranging between 5.0 × 10 −7 -1.0 × 10 −4 M and 12.5 × 10 −6 -175 × 10 −6 M, respectively, with an estimated detection limit of 1.5 × 10 −7 M and 0.11 × 10 −9 M, respectively.…”