Cu ₂ O hollow microspheres as electrode materials for non‐enzymatic electrochemical detection of glucose

Abstract

An enzyme‐free glucose electrochemical sensor with high sensitivity and selectivity is highly attractive. In this work, an enzyme‐free glucose sensor with Cu2O hollow microspheres (Cu2O HMs) was prepared via hydrothermal method. The glucose sensor constructed by the prepared Cu2O HM structure exhibited a low detection limit of 0.13 μM, a high sensitivity of 277.1 μA/mM cm2, and the wide linear ranges of 0.05–1.5 and 1.5–6.0 mM. Furthermore, anti‐interference tests indicated that the prepared sensor exhibited good selectivity for glucose and practical application in human serum. The Cu2O sensor has great application potential in the development of enzyme‐free glucose sensor.

In situ growth of self-supported CuO nanorods from Cu-MOFs for glucose sensing and elucidation of the sensing mechanism

“…In a nonenzymatic sensing system, choosing the right catalyst immobilized on the electrode, which mimics enzyme functions, is critical to ensure high sensitivity and specicity. [7][8][9][10][11][12][13] Currently, three categories of materials have proven to be good enzyme substitutions: carbon nanomaterials, metals (e.g., Pt, Au, Pd, Cu, and Ni) and metal oxides (e.g., Co 3 O 4 , NiO, and CuO). 14 Copper oxide (CuO), a well-investigated transition metal oxide, is an active material in non-enzymatic glucose sensors due to its excellent sensitivity, high stability, low cost and easy synthesis.…”

“…In a non-enzymatic sensing system, choosing the right catalyst immobilized on the electrode, which mimics enzyme functions, is critical to ensure high sensitivity and specificity. 7–13 Currently, three categories of materials have proven to be good enzyme substitutions: carbon nanomaterials, metals ( e.g. , Pt, Au, Pd, Cu, and Ni) and metal oxides ( e.g.…”