Cu(OAc)2Catalyzed Synthesis of Novel Chromeno [4,3-b]Pyrano[3,4-e]Pyridine-6,8-Dione Derivatives via a One-Pot Multicomponent Reaction in Water under Mild Reaction Conditions

Sayahi, Mohammad Hosein; Afrouzandeh, Zahra; Bahadorikhalili, Saeed

doi:10.1080/10406638.2020.1866037

Cited by 6 publications

(3 citation statements)

References 53 publications

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“…However, selecting an appropriate green solvent for a synthetic reaction depends on several factors, including the desired reaction conditions, the solubility of the reactants and products, and the environmental impact 26 . Using green solvents can help reduce the environmental impact of synthetic organic chemistry and make chemical processes more sustainable 27 …”

Section: Introductionmentioning

confidence: 99%

“…26 Using green solvents can help reduce the environmental impact of synthetic organic chemistry and make chemical processes more sustainable. 27 Polyethylene Glycol 400 (PEG-400) stands out as a revolutionary solution. 6 This readily available, non-toxic polymer possesses a unique dual role in green MCRs and traditional methods of organic transformations.…”

Section: Introductionmentioning

confidence: 99%

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Recent advances in polyethylene glycol as a dual‐functional agent in heterocycle synthesis: Solvent and catalyst

Servesh,

Lokesh Kumar,

Govindaraju

et al. 2024

Polymers for Advanced Techs

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Reactant solubility, which dictates achievable concentrations, and the stability of reaction intermediates (excited states), solvents modulate the potential energy landscape and influence reaction rates. Consequently, solvent selection is pivotal in optimizing process productivity, economic feasibility, and environmental footprint. At present, organic synthesis pivots around the idea of sustainability. In particular, PEG‐400, a popular solvent and phase transfer catalyst, is considered greener as it can be reused several times without significant loss in its catalytic activity, which checks the box regarding sustainability. This review highlights the emerging potential of Polyethylene Glycol 400 (PEG‐400) as a dual‐threat agent in sustainable organic synthesis. We explore its efficacy as a catalyst, promoting various reactions under mild conditions and often eliminating the need for traditional metal catalysts. Additionally, PEG‐400's role as a green solvent is addressed, emphasizing its biodegradability, low toxicity, and ability to facilitate reactions without hazardous Volatile Organic Compounds (VOCs). The review examines recent research on PEG‐400 mediated reactions, showcasing its effectiveness in diverse transformations, thus exploring the potential of PEG 400 as a facilitator for heterocycle synthesis in both multicomponent reactions and stepwise approaches. It identifies exciting research directions that promise to expand the boundaries of polymer‐based solvents in heterocyclic chemistry.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Recent advances in polyethylene glycol as a dual‐functional agent in heterocycle synthesis: Solvent and catalyst

Servesh,

Lokesh Kumar,

Govindaraju

et al. 2024

Polymers for Advanced Techs

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“…Multicomponent reactions are of high interest, due to several advantages including fast reaction performance, high yield of the products, and high atom efficiency [35][36][37][38] . Therefore, these kinds of reactions have been successfully applied for the synthesis of various compounds with complex structures 39,40 .…”

mentioning

confidence: 99%

Palladium supported magnetic Fucus Vesiculosus extract as a natural and novel catalyst for the synthesis of N-alkyl-2-(4-methyl-1-oxoisoquinolin-2(1H)-yl)-2-phenylacetamide derivatives

Yousefnejad

Bahadorikhalili

Esmkhani

et al. 2023

Sci Rep

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In this paper, a novel catalyst is introduced based on the immobilization of palladium onto magnetic Fucus Vesiculosus extract (Pd@mFuVe catalyst). For the synthesis of Pd@mFuVe catalyst, Fucus Vesiculosus extract is obtained from the plant source, followed by the synthesis of superparamagnetic iron oxide nanoparticles (SPION) onto the extract. The catalyst is characterized by several methods, including scanning electron microscopy (SEM), energy-dispersive X-ray spectroscopy (EDS), FT-IR spectroscopy, vibrating sample magnetometer (VSM), powder X-ray diffraction analysis (XRD), and inductively coupled plasma (ICP). The activity of Pd@mFuVe catalyst is studied in the synthesis of N-alkyl-2-(4-methyl-1-oxoisoquinolin-2(1H)-yl)-2-phenylacetamides. The products were synthesized in three steps, the synthesis of 2-iodobenzoic acid from 2-aminobenzoic acid, which participated in a multicomponent reaction with allylamine, aldehydes, and isocyanides, followed by a cyclization reaction, catalyzed by Pd@mFuVe catalyst. The product yields are high and the catalyst showed good reusability after 5 sequential runs. The most significant, Pd@mFuVe catalyst is fabricated from a plant extract source as a green support for the catalyst.

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Recent advances in the synthesis of six-membered heterocycles via multicomponent reactions (from 2017 to 2022)

Zadsirjan

2024

Advances in Heterocyclic Chemistry

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Cu(OAc)₂Catalyzed Synthesis of Novel Chromeno [4,3-b]Pyrano[3,4-e]Pyridine-6,8-Dione Derivatives via a One-Pot Multicomponent Reaction in Water under Mild Reaction Conditions

Cited by 6 publications

References 53 publications

Recent advances in polyethylene glycol as a dual‐functional agent in heterocycle synthesis: Solvent and catalyst

Recent advances in polyethylene glycol as a dual‐functional agent in heterocycle synthesis: Solvent and catalyst

Palladium supported magnetic Fucus Vesiculosus extract as a natural and novel catalyst for the synthesis of N-alkyl-2-(4-methyl-1-oxoisoquinolin-2(1H)-yl)-2-phenylacetamide derivatives

Recent advances in the synthesis of six-membered heterocycles via multicomponent reactions (from 2017 to 2022)

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