[Cu(L-prolinate)2]: A catalyst for environmentally friendly oxidation of alkanes and alkenes with H2O2 and O2

Synthesis and characterization of novel transition metal complexes with L-Proline and their catalytic activity evaluation towards cyclohexane oxidation

“…The results of the UV-visible and IR spectra suggest that the metals in all three different metal-L-proline complexes prepared are bounded with two molecules of amino acids to form an amino acid-metal complex (figure 1(A)), where (metal=Fe, Co, or Mn) with 1:2 molar ratios. This result agrees with the work on Cu 2+ ions proposed by Mascaros et al [18].…”

Aerobic Copper-Catalyzed Organic Reactions

“…These reports include: reviews (Section I), 1149,1150,1151,1152 oxygenation of unactivated benzylic substrates (Section IIA.2), 1153,1154,1155 alkane oxidation (Section II.B), 1156,1157,1158 epoxidation of alkenes (Section II.C.2), 1159 oxidation difunctionalization of alkenes (Section II.C.3), 1160,1161,1162,1163,1164 cross coupling with alkynes (Section II.D.3), 1165 oxidation difunctionalization of alkynes (Section II.D.4), 1166,1167,1168 arene hydroxylation (Section II.E.1), 1169 reactions involving nucleophilic arenes (Section II.E.2), 1170 direction insertion of arenes (Section II.E.3), 1171,1172,1173,1174,1175 functionalization of acidic arene positionos (Section II.E.4), 1176,1177,1178 coupling of carbanion equivalents with boronic acids (Section III.C), 1179,1180,1181,1182,1183,1184,1185 alcohol oxidation (Section IV.A.1),1186,1187,1188,1189,1190,1191,1192,1193,1194,1195,1196,1197,1198,1199 tandem reaction with alcohol oxidation (Section IV.D), 1200,1201,1202,1203,1204,1205,1206,1207,1208 oxidation of aldehydes to amides (Section V.A), 1209 enolate oxiation without cleavage (Section V.C), 1210,1211 oxidative coupling of enolates (Section V.C.1), 1212 α-oxygenation of carboxylic acids (Section V.E), 1213 reaction of hydrazones (Section V.G), 1214 oxidation of hydrazones with cyclization (Section V.G), 12151216 reactions of enamines (Section VI.A), 1217,…”

Introducing Copper as Catalyst for Oxidative Alkane Dehydrogenation

“…The reaction of cycloalkanes with hydrogen peroxide in the presence of transition metal complexes has been previously described by several groups, although in no case dehydrogenation was reported. It has been proposed that those transformations seem to occur under Fenton-like pathways, i.e., with the intermediacy of free hydroxyl radicals.…”

“…This is the base of the so-called Fenton chemistry, that is mainly characterized by the lack of selectivity. Since several copper compounds or salts have been reported to generate such radical promoting alkane oxidations, , we have first performed a series of experiments to elucidate whether or not our transformation occurs in a similar manner. However, we must emphasize at this point that no alkene formation has ever been described in those copper-based systems .…”