CTSS promoter -25G/A: not a risk factor for CHD in Chinese

Sun, Aijun; Rauniyar, Binay Kumar; Xiang, Feiyu; Zhao, Ji; Wang, Ying; Liu, Xu; Ma, Huili; Wang, Keqiang; Zou, Yunzeng; Huang, Wei; Ge, Junbo

doi:10.2143/ac.64.3.2038027

Cited by 9 publications

(8 citation statements)

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“…It was also found that the (h02) C spots with h = odd remain stronger than the spots with h = even in the [010] zone axis diffraction patterns of Zn and Ni doped compounds [16]. This means that the substitutions of Cu ions either by nonmagnetic Zn 2+ ions or by weak magnetic Ni 2+ ions do not induce any changes in the structure of the compound.…”

Section: Structural Transition With the Co Dopingmentioning

confidence: 96%

Structural transition, electrical and magnetic properties of the B-site Co doped Sr₁₄Cu₂₄O₄₁compounds

Wang¹,

Lin²,

H³

et al. 2009

J. Phys.: Condens. Matter

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The effect of Co substitution for Cu on the structure and physical properties of Sr(14)(Cu(1-x)Co(x))(24)O(41) compounds was studied by analyzing the selected-area electron diffraction and convergent-beam electron diffraction patterns, and by measuring the magnetic susceptibility, the electrical resistivity and Raman spectra. It is found that the space group of the CuO(2) chain is changed from Amma to Ammm upon Co doping, but the structure of the Cu(2)O(3) ladder remains unchanged. This indicates that the displacement between two neighboring CuO(2) chains has disappeared due to Co doping. Once a small amount of Co ions are doped into the compound, exceptional changes in the Weiss temperature and in the number of dimers occur. The remarkable increase in the absolute value of the Weiss temperature indicates that the antiferromagnetic interaction in CuO(2) chains becomes very strong due to Co doping. The increase in the Curie coefficient and the number of dimers implies that the Co doping causes Zhang-Rice singlets in the chains to be decoupled into free spins Cu(2+) and holes. Then, the free spins Cu(2+) are coupled into dimers, and the holes transfer from chains to ladders, which causes the resistivity to decrease when the Co dopant concentration is low (x<0.10). When the Co dopant concentration is high (x>0.10), some Co ions are directly substituted for the Cu ions in the ladders, which results in an increase in resistivity with increasing Co dopant content.

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Section: Structural Transition With the Co Dopingmentioning

confidence: 96%

Structural transition, electrical and magnetic properties of the B-site Co doped Sr₁₄Cu₂₄O₄₁compounds

Wang¹,

Lin²,

H³

et al. 2009

J. Phys.: Condens. Matter

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“…This technology holds immense potential in the field of biomedicine and is expected to be used in high-throughput drug screening, new drug development, and biophysiological research. [126] Currently, organ-on-achip systems have been developed using cardiomyocytes and skeletal muscle cells.…”

Section: Organ-on-a-chipmentioning

confidence: 99%

Biosyncretic Robots Actuated by Living Materials

Yang,

Zhang,

Wang

et al. 2023

Adv Materials Technologies

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In recent years, biosyncretic robots, a novel type of robot that integrates living and artificial materials, have gained significant attention. Biosyncretic robots are expected to leverage the advantages provided by living materials and offer a new approach to address the challenges faced by traditional robots, such as biocompatibility, intrinsic safety, and miniaturization. Therefore, this review aims to provide an overview of the current state of development of biosyncretic robots. First, the existing research on biosyncretic robots based on commonly used living materials is systematically categorized and introduced, including cardiomyocytes, skeletal muscle cells, insect dorsal vascular tissue, and microorganisms. Subsequently, their potential in the fields of in vivo medical diagnosis and treatment, organ‐on‐a‐chip, tissue engineering, environmental monitoring, and postdisaster rescue in detail is also discussed. Finally, the current challenges faced by biosyncretic robotic research, including establishing theoretical models, fabrication, cultivation, and maintenance of living materials, controllability, versatility, artificial material, and entering the human body or leaving the laboratory, are examined. This review summarizes the cutting‐edge progress of biosyncretic robots and provides insights into their future development.

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“…A key to developing in vitro 3D cell models is the capacity to replicate the extracellular matrix (ECM) of the native tissue with respect to mechanical and chemical properties. [9,10] Hydrogels, which are polymer-based structures containing a large fraction of water, offer a valuable tool to recreate human physiology in ways not possible with traditional cell culture substrates. [11] The recent development of synthetic and hybrid polymers has overcome the batch-tobatch variation of natural hydrogels with maintained cell responsive functionalities combined with mechanical stability and good processability.…”

Section: Introductionmentioning

confidence: 99%

A Perfusable Multi‐Hydrogel Vasculature On‐Chip Engineered by 2‐Photon 3D Printing and Scaffold Molding to Improve Microfabrication Fidelity in Hydrogels

Cantoni,

Barbe,

Pohlit

et al. 2024

Adv Materials Technologies

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Engineering vasculature networks in physiologically relevant hydrogels represents a challenge in terms of both fabrication, due to the cell–bioink interactions, as well as the subsequent hydrogel‐device interfacing. Here, a new cell‐friendly fabrication strategy is presented to realize perfusable multi‐hydrogel vasculature models supporting co‐culture integrated in a microfluidic chip. The system comprises two different hydrogels to specifically support the growth and proliferation of two different cell types selected for the vessel model. First, the channels are printed in a gelatin‐based ink by two‐photon polymerization (2PP) inside the microfluidic device. Then, a human lung fibroblast‐laden fibrin hydrogel is injected to surround the printed network. Finally, human endothelial cells are seeded inside the printed channels. The printing parameters and fibrin composition are optimized to reduce hydrogel swelling and ensure a stable model that can be perfused with cell media. Fabricating the hydrogel structure in two steps ensures that no cells are exposed to cytotoxic fabrication processes, while still obtaining high fidelity printing. In this work, the possibility to guide the endothelial cell invasion through the 3D printed scaffold and perfusion of the co‐culture model for 10 days is successfully demonstrated on a custom‐made perfusion system.

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CTSS promoter -25G/A: not a risk factor for CHD in Chinese

Abstract: The CTSS -25G/A polymorphism was not related with CHD in our Chinese population sample.

Cited by 9 publications

References 0 publications

Structural transition, electrical and magnetic properties of the B-site Co doped Sr₁₄Cu₂₄O₄₁compounds

Structural transition, electrical and magnetic properties of the B-site Co doped Sr₁₄Cu₂₄O₄₁compounds

Biosyncretic Robots Actuated by Living Materials

A Perfusable Multi‐Hydrogel Vasculature On‐Chip Engineered by 2‐Photon 3D Printing and Scaffold Molding to Improve Microfabrication Fidelity in Hydrogels

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CTSS promoter -25G/A: not a risk factor for CHD in Chinese

Abstract: The CTSS -25G/A polymorphism was not related with CHD in our Chinese population sample.

Cited by 9 publications

References 0 publications

Structural transition, electrical and magnetic properties of the B-site Co doped Sr14Cu24O41compounds

Structural transition, electrical and magnetic properties of the B-site Co doped Sr14Cu24O41compounds

Biosyncretic Robots Actuated by Living Materials

A Perfusable Multi‐Hydrogel Vasculature On‐Chip Engineered by 2‐Photon 3D Printing and Scaffold Molding to Improve Microfabrication Fidelity in Hydrogels

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Structural transition, electrical and magnetic properties of the B-site Co doped Sr₁₄Cu₂₄O₄₁compounds

Structural transition, electrical and magnetic properties of the B-site Co doped Sr₁₄Cu₂₄O₄₁compounds