Abstract:Objective: Connective tissue growth factor (CTGF) has a potent proliferative, differentiated, and mineral effect, and is thought to be involved in cartilage mineralization in Osteoarthritis (OA). However, little is known about the mechanism of chondrocytic mineralization that is induced by Connective tissue growth factor (CTGF). As a crucial mediator in regulating mineral responses, the type III phosphate transporter 1 (Pit-1) has been implicated in the pathogenesis of articular mineralization. The aim of this… Show more
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