CTAB assisted synthesis of MnFe2O4@ SiO2 nanoparticles for magnetic hyperthermia and MRI application

Kavkhani, Roya; Hajalilou, Abdollah; Abouzari‐Lotf, Ebrahim; Ferreira, Liliana P.; Cruz, Miguel A.; Yusefi, Mostafa; Parvini, Elahe; Ismail, Umi Nabilah

doi:10.1016/j.mtcomm.2022.103412

Cited by 14 publications

(6 citation statements)

References 68 publications

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“…Moreover, MnFe 2 O 4 , L-Cysteine, and MnFe 2 O 4 @L-Cysteine have low toxicity with the cell viability above 95%. MTT test results are in agreement with the earlier ndings on the good biocompatibility of MnFe 2 O 4 NP and L-Cysteine [68,70,71], which makes them appropriate for biomedical purposes.…”

supporting

confidence: 90%

MnFe2O4@L-Cysteine as a drug delivery system, in vitro cytotoxicity evaluation on human Breast cancer cell (MCF7) and DFT calculation

hasankhani,

Hosseini,

Askarizadeh

et al. 2024

Preprint

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Thanks to their high hydrophilic and magnetic properties, MnFe2O4 nanoparticles (NP) are recognized as favorable drug carriers. In this study, L-Cysteine-modified MnFe2O4 nanoparticles (MnFe2O4@L-Cysteine) were prepared and characterized. Their cytotoxicity against human breast cancer cell lines (MCF7) was also evaluated by MTT assay. To simulate drug delivery systems, the interaction between modified NP and 5-fluorouracil (5-FU) was examined as a breast cancer drug. The MTT results showed the applicability of MnFe2O4@L-Cysteine nanoparticles as a potential cytotoxic agent in breast cancer treatment. Based on the theoretical calculations, the adsorption energy between L-Cysteine and 5-FU was − 12.029 KJ/mol and their interaction was spontaneous and exothermic at the temperature range of 278.15 to 288.15 K. Also, the drug release thermodynamically is feasible at body temperature. The calculated electronic descriptors indicated that the electrons were transferred from L-Cysteine to 5- FU. Overall, MNFe2O4@L-Cysteine, in addition to being non-toxic has the potential to deliver 5-FU anticancer drug.

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supporting

confidence: 90%

MnFe2O4@L-Cysteine as a drug delivery system, in vitro cytotoxicity evaluation on human Breast cancer cell (MCF7) and DFT calculation

hasankhani,

Hosseini,

Askarizadeh

et al. 2024

Preprint

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“…Several other types of magnetic nanoparticles have also been utilized in magnetic hyperthermia including iron, 46 magnesium alloys, 79 Ni alloys, 80 Ni-Cr alloy, 81 Ni-Si and Ni-Al, 82 Fe-Ni alloys, 83 Fe-Co alloy, 47 FeNiCo alloys, 84 Ni-Cu alloys, 85,86 Fe-Al alloy, 87 Fe-Au alloys, 88,89 Fe 3 C nanoparticles, 71 Fe-Cr-Nb-B alloy, 90 Fe-Mn-Gd ferrite, 91 hematite (α-Fe 2 O 3 ) and nickel ferrite, 92 cobalt ferrite, [93][94][95][96][97][98][99][100][101][102][103][104][105] cobalt zinc ferrite, [106][107][108][109][110][111] Zn-Mg ferrite, 112 Mg 0.7 Zn 0.3 Fe 2 O 4 nanocrystals, 113 manganese ferrite , 44,[114][115][116][117][118] ZnMn ferrite, [119][120][121][122]…”

Section: Copper Ferritementioning

confidence: 99%

“…The magnetic nanoparticles that can be used in hyperthermia are categorized into six groups including metal oxide nanoparticles, 43 ferrite nanoparticles, 44,45 metallic nanoparticles, 46 metallic alloyed nanoparticles, 47 core/shell nanoparticles, 48 and metal-doped iron oxide nanoparticles. 3 The ferrites have received attention for hyperthermia treatment due to their superior magnetic properties, low inherent toxicity, easy synthesis, and chemical stability.…”

Section: Nanoparticles Used In Magnetic Hyperthermiamentioning

confidence: 99%

“…Several other types of magnetic nanoparticles have also been utilized in magnetic hyperthermia including iron, 46 magnesium alloys, 79 Ni alloys, 80 Ni-Cr alloy, 81 Ni-Si and Ni-Al, 82 Fe-Ni alloys, 83 Fe-Co alloy, 47 FeNiCo alloys, 84 Ni-Cu alloys, 85,86 Fe-Al alloy, 87 Fe-Au alloys, 88,89 Fe 3 C nanoparticles, 71 Fe-Cr-Nb-B alloy, 90 Fe–Mn–Gd ferrite, 91 hematite (α-Fe 2 O 3 ) and nickel ferrite, 92 cobalt ferrite, 93–105 cobalt zinc ferrite, 106–111 Zn‐Mg ferrite, 112 Mg 0.7 Zn 0.3 Fe 2 O 4 nanocrystals, 113 manganese ferrite , 44,114–118 ZnMn ferrite, 119–124 magnesium ferrite, 125–128 zinc ferrite, 45,129–133 Zn–Ni spinel ferrite, 134 Zn-doped spinel Fe 3 O 4 , 135 nickel ferrite, 136 copper ferrite, 137 copper zinc ferrite, 138 and γ-Fe 2 O 3 . 139–144…”

Section: Nanoparticles Used In Magnetic Hyperthermiamentioning

confidence: 99%

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Magnetic hyperthermia in cancer therapy, mechanisms, and recent advances: A review

Molaei

2024

J Biomater Appl

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Hyperthermia therapy refers to the elevating of a region in the body for therapeutic purposes. Different techniques have been applied for hyperthermia therapy including laser, microwave, radiofrequency, ultrasonic, and magnetic nanoparticles and the latter have received great attention in recent years. Magnetic hyperthermia in cancer therapy aims to increase the temperature of the body tissue by locally delivering heat from the magnetic nanoparticles to cancer cells with the aid of an external alternating magnetic field to kill the cancerous cells or prevent their further growth. This review introduces magnetic hyperthermia with magnetic nanoparticles. It includes the mechanism of the operation and magnetism behind the magnetic hyperthermia phenomenon. Different synthesis methods and surface modification to enhance the biocompatibility, water solubility, and stability of the nanoparticles in physiological environments have been discussed. Recent research on versatile types of magnetic nanoparticles with their ability to increase the local temperature has been addressed.

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“…nanomaterials are the most explored [ 3 , 4 , 5 , 6 , 7 , 8 , 9 , 10 ]. Nanoparticles’ properties make them appropriate applicants for technical applications in biosensors, humidity sensors, photocatalysis, magnets, drug delivery, magnetic refrigeration, magnetic liquids, photoluminescence, microwave absorbents, ceramic pigments, gas sensing, corrosion protection, water decontamination, antimicrobial agents, biomedicine, and catalysis [ 10 , 11 , 12 , 13 , 14 , 15 , 16 , 17 , 18 , 19 , 20 , 21 , 22 , 23 , 24 , 25 ]. Adjusting the nanoparticles’ shapes, sizes, and properties can be performed via the synthesis route, by modifying parameters such as the pH and concentration of reactants, dopants, or thermal treatment temperature and time [ 20 , 21 , 22 , 23 , 24 , 25 , 26 , 27 , 28 , 29 ].…”

Section: Introductionmentioning

confidence: 99%

Innovative Nanomaterial Properties and Applications in Chemistry, Physics, Medicine, or Environment

Dippong

2024

Nanomaterials

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CTAB assisted synthesis of MnFe2O4@ SiO2 nanoparticles for magnetic hyperthermia and MRI application

Cited by 14 publications

References 68 publications

MnFe2O4@L-Cysteine as a drug delivery system, in vitro cytotoxicity evaluation on human Breast cancer cell (MCF7) and DFT calculation

MnFe2O4@L-Cysteine as a drug delivery system, in vitro cytotoxicity evaluation on human Breast cancer cell (MCF7) and DFT calculation

Magnetic hyperthermia in cancer therapy, mechanisms, and recent advances: A review

Innovative Nanomaterial Properties and Applications in Chemistry, Physics, Medicine, or Environment

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