CT Signs of Right Ventricular Dysfunction

Kang, Doo Kyoung; Thilo, Christian; Schoepf, U. Joseph; Barraza, J. Michael; Nance, John W.; Bastarrika, Gorka; Abro, Joseph A.; Ravenel, James G.; Costello, Philip; Goldhaber, Samuel Z.

doi:10.1016/j.jcmg.2011.04.013

Cited by 170 publications

(50 citation statements)

References 42 publications

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“…Interventricular septal flattening, for instance, has been associated with prognosis in pulmonary hypertension and pulmonary embolism. 3 In addition, less conical right ventricular (RV) remodeling in functional tricuspid regurgitation has been suggested as a potential factor for consideration in the methodology used for tricuspid valve repair. 4 These morphologic changes, however, are difficult to characterize on two-dimensional (2D) echocardiography, because multiple imaging planes need to be integrated to appreciate the complex asymmetric crescent shape of the right ventricle, making quantitative evaluation complex and impractical.…”

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confidence: 99%

Morphologic Analysis of the Normal Right Ventricle Using Three-Dimensional Echocardiography–Derived Curvature Indices

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Maffessanti

Muraru

et al. 2018

Journal of the American Society of Echocardiography

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Background Right ventricular (RV) remodeling involves changes in size, wall thickness, function, and shape. Previous studies have suggested that regional curvature indices (rCI) may be useful for RV shape analysis. The aim of this study was to establish normal three-dimensional echocardiographic values of rCI in a large group of healthy subjects to facilitate future three-dimensional echocardiographic study of adverse RV remodeling. Methods RV endocardial surfaces were reconstructed at end-diastole and end-systole in 245 healthy subjects (mean age, 42 ± 12 years) and analyzed using custom software to calculate mean curvature in six regions: RV inflow tract (RVIT) and RV outflow tract, apex, and body (both divided into free wall and septal regions). Associations with age and gender were studied. Results The apical free wall was convex, while the septum (apex and body) was more concave than the body free wall. Septal curvature did not change significantly from end-diastole to end-systole. The RV outflow tract and RVIT became flatter from end-diastole to end-systole. In keeping with the “bellows-like” action of RV contraction, the body free wall became flatter, while the apex free wall changed to a more convex surface. There were no intergender differences in rCI. In older subjects (≥55 years of age), the RV free wall and RV outflow tract were flatter, and from end-diastole to end-systole, the RVIT became less flattened and the apex less pointed. These changes suggest that the right ventricle is stiffer in older subjects, with less dynamic contraction of the RVIT and less bellows-like movement. Conclusions This study established normal three-dimensional echocardiographic values for RV rCI, which are needed to further study RV diastolic dysfunction and remodeling with disease.

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confidence: 99%

Morphologic Analysis of the Normal Right Ventricle Using Three-Dimensional Echocardiography–Derived Curvature Indices

Addetia

Maffessanti

Muraru

et al. 2018

Journal of the American Society of Echocardiography

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“…Evaluating the prognosis of pulmonary embolism in children using CT pulmonary angiography has been sparsely studied. The CT pulmonary angiography prognostic parameters found in adults [47, 48] have the potential to be used as important tools when assessing the prognostic utility of CT pulmonary angiography in children.…”

Section: Ct Findings Of Acute Pulmonary Embolismmentioning

confidence: 99%

Multidetector computed tomography pulmonary angiography in childhood acute pulmonary embolism

et al. 2015

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Pulmonary embolism is a life-threatening condition affecting people of all ages. Multidetector row CT pulmonary angiography has improved the imaging of pulmonary embolism in both adults and children and is now regarded as the routine modality for detection of pulmonary embolism. Advanced CT pulmonary angiography techniques developed in recent years, such as dual-energy CT, have been applied as a one-stop modality for pulmonary embolism diagnosis in children, as they can simultaneously provide anatomical and functional information. We discuss CT pulmonary angiography techniques, common and uncommon findings of pulmonary embolism in both conventional and dual-energy CT pulmonary angiography, and radiation dose considerations.

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“…The ratio of the MPA diameter to that of the aorta was also calculated. Contrast reflux to the inferior vena cava (IVC) and convex leftward ventricular septal bowing (VSB) were also evaluated [6].…”

Section: Ct Analysismentioning

confidence: 99%

“…Patients with acute PE who also have right ventricular dysfunction (RVD) have a worse prognosis [5]. Although echocardiography (ECHO) performed at bedside is the imaging modality of choice for demonstration of RVD, for unstable patients CTPA has recently replaced ECHO for this purpose, because of its high accuracy and 24-h availability in most healthcare centers [6]. CTPA enables heart chamber quantification and has thus been increasingly preferred for evaluation of right ventricular (RV) function in acute PE, and is an attractive alternative to ECHO [7].…”

Section: Introductionmentioning

confidence: 99%

The efficacy of CT for detection of right ventricular dysfunction in acute pulmonary embolism, and comparison with cardiac biomarkers

et al. 2015

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CT Signs of Right Ventricular Dysfunction

Cited by 170 publications

References 42 publications

Morphologic Analysis of the Normal Right Ventricle Using Three-Dimensional Echocardiography–Derived Curvature Indices

Morphologic Analysis of the Normal Right Ventricle Using Three-Dimensional Echocardiography–Derived Curvature Indices

Multidetector computed tomography pulmonary angiography in childhood acute pulmonary embolism

The efficacy of CT for detection of right ventricular dysfunction in acute pulmonary embolism, and comparison with cardiac biomarkers

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