This is a review of the literature related to the progress in the management of intussusception. Literature and other publication on the topic of “intussusception” were retrieved from 1674 to August 2021. The online literature search was – performed using various websites, i e, PubMed, PubMed central, ResearchGate, and Google - eBooks, Google Scholar, and Google Images. The important historical events that occurred in the management of intussusception were briefly presented in this manuscript.