CT of adenoid cystic carcinoma of the trachea

Spizarny, David L.; Shepard, Jo Anne O.; McLoud, Theresa C.; Grillo, Hermes C.; Dedrick, Carolyn G.

doi:10.2214/ajr.146.6.1129

Cited by 55 publications

(13 citation statements)

References 6 publications

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“…'~~'~ CT is also a poor predictor of mediastinal organ invasion. 16 In 92% (1 1/ 12) of cases, the tumor masses were well demonstrated. However, sometimes small tumors in the lumen of the trachea are visible only with CT images at lung window settings and could be missed at soft tissue window settings (Fig.…”

Section: Discussionmentioning

confidence: 94%

Primary malignant tumors of the trachea. A radiologic and clinical study

Ellerbroek

Libshitz

1990

Cancer

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Fifty-four cases (55 foci) of primary tracheal malignancies were reviewed retrospectively. Radiologic material was available in 32 cases (33 tracheal foci). The most frequent primary malignant tumor of the trachea was squamous cell carcinoma (54.5%), followed by adenoid cystic carcinoma (18%) and adenocarcinoma (9%). The radiologic appearance of the tumors could be divided into intraluminal, wall-thickening, and exophytic forms. Wall-thickening and exophytic forms in this study accounted for 62% of the tumors. This indicates that malignant tumors of the trachea tend to extraluminal invasion. Tomography and computed tomography are the most helpful methods of radiologic examination for tracheal tumors. Bronchoscopy and radiologic examination are complementary procedures. The chief advantage of imaging is the demonstration of tracheal wall thickening and extraluminal changes. Hemoptysis, dyspnea, and cough were the most common symptoms. Four cases (7%) in our series presented as thyroid tumors due to direct extension into the thyroid gland. Fifteen of the 54 cases (28%) were associated with other carcinomas of the head and neck and the lung.

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Section: Discussionmentioning

confidence: 94%

Primary malignant tumors of the trachea. A radiologic and clinical study

Ellerbroek

Libshitz

1990

Cancer

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“…Primary salivary gland–type tumors of the lung, particularly ACC and high-grade MEC, are infiltrative, and the amount of submucosal infiltration is often difficult to assess preoperatively and during surgery. Although single-detector CT scanners consistently underestimated the longitudinal extent of lesions [14], the introduction of MDCT with multiplanar reconstruction ability has improved the evaluation of the extent of tumors in airways [2, 3]. Because ACC is notorious for submucosal infiltration and, as shown in our study, is more likely to present with higher FDG uptake, it seems intuitive that one could better delineate the extent of tumor with FDG uptake and thereby improve preoperative estimation of tumor extent.…”

Section: Discussionmentioning

confidence: 99%

Primary Salivary Gland–Type Lung Cancer: Imaging and Clinical Predictors of Outcome

ElNayal¹,

Moran

Fox

et al. 2013

American Journal of Roentgenology

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OBJECTIVE The objective of our study was to assess whether CT features and FDG uptake of primary salivary gland–type tumors of the lung are associated with tumor type, disease stage, or survival. MATERIALS AND METHODS CT (n = 30) and PET (n = 15) data of 30 consecutive patients with primary salivary gland–type tumors of the lung were retrospectively evaluated for tumor size, location, and homogeneity and the presence of lymphadenopathy, pleural effusions, and metastases. Maximum FDG uptake and volumetric FDG uptake of the tumors were recorded. The Wilcoxon rank sum and Fisher exact tests and univariate Cox regression were used for statistical calculations. RESULTS Compared with mucoepidermoid carcinomas, adenoid cystic carcinomas (57%) were larger (mean, 3.5 vs 2.2 cm, respectively; p = 0.03), more frequently involved the central airways (94% vs 63%; p = 0.002), and had a higher median FDG uptake (p = 0.0264). Higher FDG uptake of the primary tumor was associated with nodal tumor involvement (p = 0.05). The median overall survival times for patients with adenoid cystic carcinoma and mucoepidermoid carcinoma were 7.7 and 4.0 years, respectively. Imaging features that significantly affected overall survival included the presence of mediastinal or hilar lymphadenopathy (hazard ratio [HR], 4.33; 95% CI, 1.15–16.26; p = 0.03), suspected metastatic disease (HR, 5.10; 95% CI, 1.27– 20.47; p = 0.02), and primary tumor heterogeneity (HR, 3.46; 95% CI, 1.04–11.55; p = 0.04). CONCLUSION Higher FDG uptake is associated with nodal disease in patients with primary salivary gland–type tumors of the lung but is not predictive of survival, whereas CT features suggestive of advanced disease correlate with worse outcome.

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“…Computed tomography (CT) with routine axial, coronal and sagittal projections is a precise imaging modality that demonstrates tracheobronchial tumors or extrinsic masses reliably to the systematic reader. In a study of six cases of ACC, CT consistently demonstrated extramural extent of disease; however, the longitudinal extent and invasion of adjacent mediastinal structures was underestimated (15). Recent imaging advances, including multiplanar reformatting and 3D rendering, have improved CT resolution, though the quality of virtual bronchoscopy rendering of CT images does not yet approach clinical bronchoscopy (16).…”

Section: Imagingmentioning

confidence: 99%

Overview of malignant tracheal tumors

Madariaga

Gaissert

2018

Ann. Cardiothorac. Surg.

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Malignant airway tumors present particular challenges for surgeons, namely: to distinguish symptoms from those of the more frequent benign airway diseases; to separate metastatic disease from the uncommon primary tumors; and to consider curative resection in appropriate candidates. Here, we present a critical review of tracheal malignant obstruction, focusing on the evaluation of a patient with malignant airway tumor, patient selection for resection and the predictors of long-term survival. The new development in primary tracheal tumors is an old story, that of making physicians aware that resection rates in epidemiologic studies remain low, mainly because opportunities for resection are missed.

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CT of adenoid cystic carcinoma of the trachea

Cited by 55 publications

References 6 publications

Primary malignant tumors of the trachea. A radiologic and clinical study

Primary malignant tumors of the trachea. A radiologic and clinical study

Primary Salivary Gland–Type Lung Cancer: Imaging and Clinical Predictors of Outcome

Overview of malignant tracheal tumors

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