CT features associated with underlying malignancy in patients with diagnosed mesenteric panniculitis

Grégory, Jules; Dana, Jérémy; Yang, Isaac; Chong, Jaron; Drevon, Louis; Ronot, Maxime; Vilgrain, Valérie; Reinhold, Caroline; Gallix, B.

doi:10.1016/j.diii.2022.06.009

Cited by 5 publications

(2 citation statements)

References 33 publications

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“…B. Coulier опубликовал критерии КТ-визуализации с пятью рентгенологическими признаками, которые впоследствии были приняты многими авторами и использовались во многих других исследованиях для диагностики склерозирующего мезентерита (рис. 5) [91,92].…”

Section: инструментальная диагностикаunclassified

Sclerosing mesenteritis as a surgical problem: a review of the literature and own clinical observation

Bogachev,

Boldin,

Golosnitskiy

et al. 2024

Ambulatornaya khirurgiya

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The problem of studying the pathology of mesenteric fat of the small intestine in surgical practice has not yet received enough attention. A number of questions remain unresolved regarding the etiology and pathogenesis of mesenteric diseases, their possible connection with benign and malignant diseases, methods of their laboratory and instrumental diagnosis, possible options for conservative and surgical treatment, as well as systematization and structuring of the classification. One of the poorly studied representatives of diseases of the mesentery of the small intestine continues to be Sclerosing mesenteritis, characterized by various histological variants of damage to mesenteric fat and a varied nonspecific clinical picture. Taken together, this leads to certain difficulties in diagnosis, patients seeking access to doctors of various profiles, which ultimately negatively affects the results of treatment and can lead to social maladjustment and possible disability. Reports on the occurrence of this pathology in the medical literature are few and, as a rule, describe extremely rare clinical cases. However, in recent years, the frequency of detection of this pathology continues to grow steadily, which is associated with the progressive aging of the population, a high degree of surgical activity in relation to urgent diseases of the abdominal organs, and the improvement of instrumental diagnostic methods. Issues of etiology, pathogenesis, differential diagnosis of this disease and its possible connection with the paraneoplastic process currently continue to cause debate. Further accumulation of clinical experience, a better understanding of the pathogenesis of the disease, and improvement of imaging techniques will allow us to develop clearer diagnostic and clinical criteria, narrow the diagnostic search and, ultimately, improve and standardize treatment. The article provides a review of the literature on this rare surgical pathology, presents our own clinical observation, and discusses diagnostic issues and treatment options for this disease.

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Section: инструментальная диагностикаunclassified

Sclerosing mesenteritis as a surgical problem: a review of the literature and own clinical observation

Bogachev,

Boldin,

Golosnitskiy

et al. 2024

Ambulatornaya khirurgiya

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“…Mesenteric lymph nodes are usually <10 mm in MP, and the presence of larger lymph nodes warrants evaluation by either biopsy or positron emission tomography (PET-CT) [ 11 ]. It is also important to note that the presence of an MP soft-tissue nodule >10 mm and associated lymphadenopathy in another abdominopelvic region warrant further workup to rule out an underlying malignancy in patients with MP [ 44 ]. Other differential diagnoses are inflammatory pseudo-tumor, desmoid tumor, or pancreatitis.…”

Section: Diagnosismentioning

confidence: 99%

Mesenteric Panniculitis

Azar,

Ibrahim,

El Kouzi

et al. 2024

Inflamm Intest Dis

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Background: Mesenteric panniculitis (MP) is an uncommon non-neoplastic idiopathic inflammation of adipose tissue, mainly affecting the mesentery of the small intestine, with its etiology remaining largely speculative. The difference in prevalence of MP among females and males varies across multiple studies. In most cases, MP is asymptomatic; however, patients can present with nonspecific abdominal symptoms or can mimic underlying gastrointestinal and abdominal diseases. The diagnosis is suggested by computed tomography and is usually confirmed by surgical biopsies if necessary. Treatment is generally supportive and based on a few selected drugs, namely, nonsteroidal anti-inflammatory drugs or corticosteroids. Surgery is reserved when the diagnosis is unclear, when malignancy is suspected or in the case of severe presentation such as mass effect, bowel obstruction, or ischemic changes. Summary: MP is a rare inflammatory condition of the mesentery often asymptomatic but can cause nonspecific abdominal symptoms. Diagnosis relies on computed tomography imaging, with treatment mainly supportive, utilizing medications like nonsteroidal anti-inflammatory drugs or corticosteroids, while surgery is reserved for severe cases or diagnostic uncertainty. Key Messages: MP causes abdominal pain, and it is mainly diagnosed with CT scan.

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