CT evaluation of wall thickening in the alimentary tract.

Desai, R K; Tagliabue, James R.; Wegryn, Scott A.; Einstein, David M.

doi:10.1148/radiographics.11.5.1947313

Cited by 108 publications

(63 citation statements)

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“…A wall thickness greater than 5mm is considered abnormally thick [31] given that the distended wall of the esophagus is usually less than 3 mm [32] . Esophageal wall thickness asymmetry is a classic but nonspecific CT finding of esophageal cancer and esophageal wall thickness symmetry should always be considered when evaluating the esophagus by CT. CT has been shown to be less accurate when compared to other assessment modalities such as EUS [33] .…”

Section: T Stage Of Esophageal Cancermentioning

confidence: 99%

Esophageal cancer: A Review of epidemiology, pathogenesis, staging workup and treatment modalities

Napier

Scheerer

Misra

2014

WJGO

695

604

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of current treatment include surgery, radiation and chemotherapy. Tumor markers of esophageal cancer are an advancing area of research that could potentially lead to earlier diagnosis as well as playing a part in assessing tumor response to therapy. Key words: Esophageal cancer; Esophageal cancer staging; Esophageal squamous cell carcinoma; Esophageal adenocarcinoma; Surgery Core tip: Esophageal carcinoma is a serious malignancy with regards to mortality and prognosis, and is expected to increase in incidence over the next 10 years. Squamous cell carcinoma is the most common histological type of esophageal cancer worldwide but the incidence of esophageal adenocarcinoma has dramatically increased in the past 40 years. Esophageal cancer is staged according to the TNM system. Common imaging modalities used in staging include computed tomography, endoscopic ultrasound and positron emission tomography scans. Current treatment options include multimodality therapy. Including surgery, radiation and chemotherapy. Tumor markers of esophageal cancer are an advancing area of research that could potentially lead to earlier diagnosis.Napier KJ, Scheerer M, Misra S. Esophageal cancer: A Review of epidemiology, pathogenesis, staging workup and treatment modalities. World J Gastrointest Oncol 2014; 6(5): 112-120 Available from:

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Section: T Stage Of Esophageal Cancermentioning

confidence: 99%

Esophageal cancer: A Review of epidemiology, pathogenesis, staging workup and treatment modalities

Napier

Scheerer

Misra

2014

WJGO

695

604

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“…[2][3][4][5][6][7][8][9][10][11][12] In addition, several reports in the literature have attempted to differentiate benign and malignant cases of BWT. [13][14][15] These studies are relatively small and, as yet, no consensus has emerged on how this issue should be tackled.…”

Section: General Surgerymentioning

confidence: 99%

Computed tomography findings of bowel wall thickening: its significance and relationship to endoscopic abnormalities

Uzzaman

Alam

Nair

et al. 2012

annals

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INTRODUCTION The aim of this study was to conduct retrospective analysis of abdominopelvic computed tomography (CT) reports, identifying those patients in whom bowel wall thickening (BWT) was observed, and to correlate these reports with subsequent endoscopic evaluation. METHODS Formal reports for all patients undergoing abdominopelvic CT between February 2007 and September 2009 were reviewed. Where patients were identified as having colorectal 'wall thickening', results of subsequent endoscopic evaluations were documented. Only those patients with a report of BWT who had follow-up endoscopy (colonoscopy, sigmoidoscopy) were included in the analysis. RESULTS A total of 165 patients were included. Abnormalities on endoscopy at the exact site of the BWT on CT were found in 95 patients (57.58%); in 36 cases (21.82%) this was a malignant lesion. BWT of the transverse colon was significantly more likely to correspond to an endoscopic finding of cancer than other sites (p=0.034). Rectal bleeding was reported significantly more often in patients with BWT and neoplastic disease on endoscopy compared with those with normal endoscopy (p=0.04). Excluding patients with inflammatory/diverticular lesions, 59.02% of Caucasians had a neoplastic lesion at the site of reported BWT, significantly higher than the other ethnic groups (p=0.008). There were 38 patients (23.03%) who did not present with bowel symptoms and, of these, 6 were diagnosed subsequently with colorectal cancer. CONCLUSIONS This study supports endoscopic evaluation to investigate patients with CT evidence of BWT, especially in cases involving the transverse colon, in Caucasian patients or in association with symptoms of rectal bleeding.

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“…Although the clinical significance of this finding is being disputed, it has been reported to reflect mainly inflammatory bowel disease, bowel ischemia or colorectal carcinoma (1,2). However, it may also represent an incidental finding or an artifact without clinical significance (3).…”

mentioning

confidence: 99%

Incidental Colorectal Computed Tomography Abnormalities: Would You Send every Patient for a Colonoscopy?

Stermer

Lavy

Rainis

et al. 2008

Canadian Journal of Gastroenterology

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METHODS: Ninety-four consecutive patients found to have largebowel abnormalities on abdominal CT were referred for colonoscopy. Of these patients, 48 were referred for a suspected colorectal tumour and 46 for CRWT. Colonoscopy was performed and findings were compared. RESULTS: Of the 48 suspected colorectal tumours, 34 were determined to be neoplastic lesions on colonoscopy. Of these, 26 were malignant and eight were benign. Colonoscopy revealed no abnormality in 30 of 46 patients with CRWT as a solitary finding, and revealed some abnormality in 16 patients (12 had diverticular disease, four had benign neoplastic lesions). CONCLUSIONS: CRWT as an incidental and solitary finding on CT should not be regarded as a pathology prompting a colonoscopy. Approximately two-thirds of the patients had a normal colonoscopy and the remaining patients had benign lesions (12 had diverticular disease and four had benign neoplastic lesions). However, many of these patients seem to warrant colonoscopy regardless of CT findings, particularly patients who have a family history of colorectal cancer, have positive fecal occult blood test results or who are older than 50 years of age.

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CT evaluation of wall thickening in the alimentary tract.

Cited by 108 publications

References 0 publications

Esophageal cancer: A Review of epidemiology, pathogenesis, staging workup and treatment modalities

Esophageal cancer: A Review of epidemiology, pathogenesis, staging workup and treatment modalities

Computed tomography findings of bowel wall thickening: its significance and relationship to endoscopic abnormalities

Incidental Colorectal Computed Tomography Abnormalities: Would You Send every Patient for a Colonoscopy?

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