CT evaluation of hepatic tumors: comparison of CT with arterial portography, CT with infusion hepatic arteriography, and simultaneous use of both techniques.

Irie, Toshiyuki; Takeshita, Koji; Wada, Yuji; Kusano, Shoichi; Terahata, Shintarou; Tamai, Setsuo; Hatsuse, Kazuo; Aoki, Hideki; Sugiura, Yasoo

doi:10.2214/ajr.164.6.7754883

Cited by 67 publications

(23 citation statements)

References 7 publications

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“…Several studies have reported that CTAP is considered to be the most sensitive technique for the detection of hepatic tumors [13,14], however, this technique is costly, invasive and has a high false-positive rate [15,16]. There are several studies indicating that the combined use of CTAP and CTHA for patients with cirrhosis would be helpful in accurate diagnosis of small nodules [19][20][21][22], and is beneficial in the preoperative evaluation of patients with HCC [23]. Hitherto, no definitive cohort study using a large number of patients has been reported.…”

Section: Discussionmentioning

confidence: 99%

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Outcome of small liver nodules detected by computed tomographic angiography in patients with hepatocellular carcinoma

et al. 2010

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Purpose Hepatic lesions identified by computed tomography (CT) during arterial portography (CTAP) or CT hepatic arteriography (CTHA) in hepatocellular carcinoma (HCC) patients are sometimes too small to be diagnosed as HCC. We undertook this cohort study to assess whether these small lesions are actually HCC, and to clarify the effectiveness of these imaging examinations in a clinical setting. Methods We assessed the characteristics of 74 tiny lesions detected by CTAP and/or CTHA, but not by CT in 67 patients. Results Seven out of 10 nodules were histologically confirmed as HCC and 18 out of 64 lesions increased in size and showed typical findings of HCC during the followup period. Multivariate analysis revealed that the size of the main tumor ([30 mm in diameter) was associated with the presence of tiny additional HCC lesions (P = 0.002). Conclusions These findings indicate that CTAP and CTHA are recommended for determining the stage of HCC, especially when the HCC nodule is larger than 30 mm in diameter.

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Section: Discussionmentioning

confidence: 99%

“…The combined use of CTAP and CTHA was reported to be superior to CTAP or CTHA alone for detecting hepatic tumors [19][20][21][22]. Therefore, all patients received both CTAP and CTHA in this study.…”

Section: Imaging Proceduresmentioning

confidence: 99%

Outcome of small liver nodules detected by computed tomographic angiography in patients with hepatocellular carcinoma

et al. 2010

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“…CTHA is performed with the catheter in the hepatic artery [13,14]. This technique is superb in analyzing neovascularity of hepatic neoplasms.…”

Section: Ct Hepatic Arteriographymentioning

confidence: 99%

“…This technique is superb in analyzing neovascularity of hepatic neoplasms. On CT images obtained with this technique, malignant hepatic neoplasms appear as peripherally or homogeneously enhancing hyperdense masses compared with the normal hepatic parenchyma [13,14] (fig. 5b), although these tumors may appear hypoattenuating on conventional helical liver CT.…”

Section: Ct Hepatic Arteriographymentioning

confidence: 99%

Imaging of the Liver by Helical CT and MR Imaging

Yamashita¹,

Morishita²,

Awai³

et al. 2004

Intervirology

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With modern imaging technologies, including helical CT and MR imaging, the evaluation of liver morphology, blood flow and detection and characterization of liver neoplasms is possible in a noninvasive manner. Experiences in numerous institutions have established that both imaging methods are highly accurate in diagnosing hepatic pathology. Three-dimensional evaluation is feasible with fast imaging techniques such as multislice CT. With tissue-specific MR contrast agents such as SPIO, our capability is enhanced not only with respect to lesion detection but also lesion characterization.

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“…5), or localization in sites with a high propensity for pseudolesions. Combining CTHA with CTAP generally helps to increase the specificity that would be obtained with CTAP alone [10,13,[17][18][19][20]. Kanematsu et al reported nonpathological focal enhancement on helical CTHA in 31 patients suspected of having liver tumors and analyzed the frequency, size, shape, and relationship with findings on CTAP [10].…”

Section: Figmentioning

confidence: 99%

Focal attenuation differences in pericystic liver tissue as seen on CT hepatic arteriography and CT arterial portography: observation using a unified helical CT and angiography system

et al. 1999

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CT evaluation of hepatic tumors: comparison of CT with arterial portography, CT with infusion hepatic arteriography, and simultaneous use of both techniques.

Cited by 67 publications

References 7 publications

Outcome of small liver nodules detected by computed tomographic angiography in patients with hepatocellular carcinoma

Outcome of small liver nodules detected by computed tomographic angiography in patients with hepatocellular carcinoma

Imaging of the Liver by Helical CT and MR Imaging

Focal attenuation differences in pericystic liver tissue as seen on CT hepatic arteriography and CT arterial portography: observation using a unified helical CT and angiography system

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