A Al-Adsani, MH Dahniya, A Al-Beltagi, Mediastinal Widening Due to Lipomatosis and Herniated Liver and Stomach. 2000; 20(3-4): [288][289][290] Mediastinal widening on a conventional chest radiograph is a common and often challenging clinical problem. It may be due to a number of conditions, which may either be benign or malignant, normal or unusual. Computed tomography (CT) is now the initial, and in most instances, the definitive imaging modality for evaluating a widened mediastinum. We report here a case of an obese woman in whom mediastinal widening was due not only to mediastinal lipomatosis, but also to a large anterior abdominal wall defect through which the stomach and liver had herniated. We also briefly review some aspects of mediastinal widening.
Case ReportA 51-year-old hypertensive woman presented with a one-month history of progressive exertional dyspnea, snoring and inability to lie flat. She gave a three-year history of assumed bronchial asthma, for which she was irregularly taking inhaled bronchodilator and steroids. Clinical examination revealed a very obese woman (weight 110 kg), with a need to sit in a propped up position. Her blood pressure was 150/90 mm Hg, and there were no other abnormal findings in the cardiovascular and respiratory systems. The abdomen was fatty and pendulous, with a supraumbilical hernia and a lower abdominal cesarian scar. Hematological and biochemical investigations were all normal, except for fasting serum glucose of 7.1 mmol/L (normal 3.9-6.1) and total cholesterol of 5.32 mmol/L (normal 3.9-5.2). The ECG record showed a sinus regular rhythm with inverted T in L1 and aVL. A posteroanterior chest radiograph revealed moderate cardiomegaly, a dilated and unfolded aorta, narrowing of the coronal diameter (9.6 mm) of the intrathoracic portion of the trachea (normal range 14.4 to 18.2 mm in women), with a slight tracheal shift to the right and widening of the mediastinum (Figure 1), which was further evaluated by contrast-enhanced CT scan. Conventional 10 mm axial images were acquired from apex to base on a helical scanner (GE Sytex 2000, GE Medical Systems, Milwaukee, USA), following intravenous injection of 100 mL of Omnipaque (350 mgI/mLNycomed). CT of the chest showed the excessive fat surrounding the upper and mid-mediastinal structures ( Figures 2 and 3, respectively). In addition to the obvious mediastinal and abdominal lipomatosis, there was a large defect of the upper anterior abdominal wall (remote from the lower cesarian scar), through which a large part of the liver and stomach had herniated (Figures 4 and 5). These herniated structures were contributing significantly to the mediastinal widening in addition to the lipomatosis. There was cardiomegaly but the lungs were normal. Echocardiogram revealed normal systolic and impaired diastolic function of the left ventricle (ejection fraction was 70%), with left ventricular hypertrophy, mild mitral regurgitation, and mild enlargement of left atrium. She was advised to reduce her weight, and her blood pressure was ...