CT demonstration of calcification in carcinoma of the lung.

Mahoney, Mary C.; Shipley, Ralph; Corcoran, H L; Dickson, Bryan A.

doi:10.2214/ajr.154.2.2153329

Cited by 111 publications

(57 citation statements)

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“…Complete or central calcification is indicative of a benign process, while eccentric or numerous tiny amorphous calcifications are suggestive of the process being malignant [32]. Calcifications are observed in about 10% of cancers; unfortunately, these may include large, central calcifications (Fig.…”

Section: Calcificationsmentioning

confidence: 99%

“…Calcifications are observed in about 10% of cancers; unfortunately, these may include large, central calcifications (Fig. 2) [32].…”

Section: Calcificationsmentioning

confidence: 99%

“…Round lesions with smooth margin are on the other end of the malignancy spectrum [33]. Triangular lesions in subpleural and perifissural locations usually correspond to normal, intrapulmonary lymph nodes [32]. Solid lesion surrounded by a halo ground glass-opacity is usually observed in the course of inflammatory disorders, commonly in angioinvasive aspergillosis; however, such findings may also be observed for metastases of melanoma or for adjacent pulmonary parenchyma being infiltrated by the primary lung tumor [34].…”

Section: Morphologymentioning

confidence: 99%

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Solitary Pulmonary Nodule—The Role of Imaging in the Diagnostic Process

Paśnik¹,

Bestry²,

Roszkowski‐Śliż³

2017

Advances in Respiratory Medicine

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A solitary pulmonary nodule is a round opacity less than 30 mm in diameter surrounded by normally aerated lung tissue. Determination of the character of the lesion following its detection (particularly when the identification was incidental) may require a complex diagnostic process. In most cases, nodules are benign in character; however, the probability of malignancy increases significantly for part-solid lesions. The main features that describe the solitary pulmonary nodule in computed tomography scans include their size, shape, density, presence of calcification and rate of growth. PET-CT examination provides additional information on the metabolic activity of the lesions, and MRI is helpful in assessment of local invasion of surrounding structures. Due to limited availability and highly specialized character, these examinations are not routinely used. Therefore, despite development of other imaging modalities, computed tomography remains the most important and crucial diagnostic tool. Clinical risk factors such as age or smoking status are very important for evaluation of the likelihood of malignancy of a nodular lesion. Due to the multidisciplinary nature of data required for complex assessment of a solitary nodular lesion, management routines are needed in the diagnostic process such as those proposed by the Fleischner Society.

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Section: Calcificationsmentioning

confidence: 99%

“…Calcifications are observed in about 10% of cancers; unfortunately, these may include large, central calcifications (Fig. 2) [32].…”

Section: Calcificationsmentioning

confidence: 99%

Section: Morphologymentioning

confidence: 99%

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Solitary Pulmonary Nodule—The Role of Imaging in the Diagnostic Process

Paśnik¹,

Bestry²,

Roszkowski‐Śliż³

2017

Advances in Respiratory Medicine

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“…Recently several papers on detection of calcification in malignant nodules with CT have been published (1 7-19) . M따lO ney et al (19) , in their CT study with 353 malignant nodules, observed 20 nodules (6%) containing calcification. Patterns of calcification were amorphous (eight nodules), punctate (1 0 nodules) , and reticular (two nodules).…”

Section: Discussionmentioning

confidence: 96%

Active solitary tuberculoma of the lung:CT and clinical findings

Lee¹,

Kim²,

Cho³

et al. 1993

J Korean Radiol Soc

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Departmeη t 0/ Radiology, College 0/ Medicine, Soonchunhyaη~g uη iversity -AbstractTo present CT and clinical features of active tuberculomas, we analyzed retrospectively CT findings of 14 tuberculomas (n = 14) in 13 patients which appeared as solitary pulmon aη nodules on plain radiographs and evaluated the response of tuberculomas to antituberculous chemotherapy. Nine tuberculomas (64%) were ovoid in shape and 10 (72 %) showed smooth margin. Twelve (86%) tuberculomas were shown as low density lesions on unenhanced or enhanced CT scans. Calcification and cavitation were noted in three (21 %) and eight (57%) tuberculomas respectively. Seven (50%) tuberculomas were accompanied by sateJlite nodules. Acid-fast bacilli (AFB) was positive in aJl tuberculomas in sputum, lavage f1uid , or percutaneous transthoracic needle aspiration (PTNA). Smear and culture of lavage f1 uid and PTNA aspirate were superior to the detection of AFB than sputum exa 없mi 피 ina 따 t 디ion. Fo 이110 아、 w ' v' μ-매 p study with antituberculous chemotherapy in 14 tuberculomas resulted in complete disappearance in three, decrease in size in seven, and no visible change in the remaining four. These observations suggest that tuberculomas are well-defined, ovoid, and low-density nodules containing calcifications andjor cavitations. Tuberculomas are relatively indolent even with threatment.

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“…In addition, ll cases also had a past history of pulmonary tuberculosis, making it likely that calcified scar tissues of old pulmonary tuberculosis were involved in these cases. Main tumor size was 3 or more cm in all cases and calcified tumors tended to be large (2,3). Regarding the morphological characteristics, it is reported that calcification of lung cancer frequently occurs in an uneven and multiple fashion (5).…”

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confidence: 99%