CT Colonography to exclude colorectal cancer in symptomatic patients

Abstract

CTC has a high sensitivity and negative predictive value in excluding a CRC in patients with colorectal symptoms.

Post-imaging colorectal cancer or interval cancer rates after CT colonography: a systematic review and meta-analysis

“…‡Than et al 38 included patients with a new colonography diagnosis and identified those with CT colonography in the previous 3 years. 30,31,35,41 not used at all in two (17%) of 12 studies, 39,42 and its use was not reported by one (8%) study. 38 Seven (58%) of 12 studies did not report radiologist experience, four (33%) of 12 studies used radiologists with varying amounts of experience, and in one (8%) of 12 studies 37 the radiologists had previous experience of fewer than 100 cases.…”

“…Characteristics of included studies 30,31,[33][34][35][36][37][38][39][40][41][42] are shown in table 1. Most were retrospective (nine studies 33,[35][36][37][38][39][40][41][42] ) and done at a single centre (nine studies 33,[35][36][37][38][39][40]42 38 all patients with post-test colorectal cancer were included, rather than only those having CT colonography. The sex and age range of included patients was only reported in seven (58%) of 12 studies; 30,31,35,36,[38][39][40] CT colonography technique was inconsistently reported (table 1).…”

Computed tomographic colonography (CTC); colorectal cancer diagnosis with CTC in an Auckland population

“…There is now a significant body of data in the literature, accumulated over the past 15 years, which confirms the value of CTC in diagnosing CRC, both in the screening situation and in symptomatic individuals …”

“…There is now a significant body of data in the literature, accumulated over the past 15 years, which confirms the value of CTC in diagnosing CRC, both in the screening situation and in symptomatic individuals. [1][2][3][4][5][6][7] This study, from one institution, has endeavoured to follow similar methodology to the previously published series of NZ studies to determine the accuracy of investigations used for detection of CRC. [7][8][9] Our population comprised mainly (84%) symptomatic patients, while the other studies comprised all symptomatic patients.…”

“…1 CTC is a safe procedure with a lower perforation rate compared with colonoscopy. 2 There is a large quantity of data available internationally regarding sensitivity of CTC for both cancer detection and extracolonic findings [3][4][5][6] but limited data as yet from New Zealand (NZ). The aim of our study is to assess the miss rate of CTC for CRC in our institution and to compare these findings with those obtained in similar evaluations of CTC, barium enema and colonso-copy in NZ.…”