Abstract:CT colonography has the potential to become an accepted technique for evaluation of the nonvisualized part of the colon after incomplete colonoscopy, and it can increase the diagnostic yield of masses and clinically important polyps in this part of the colon.
“…Previous studies on CTC after incomplete colonoscopy have been conducted [6][7][8][9][10] . These studies were inhomogeneous regarding the patients' selection, because they included asymptomatic as well as symptomatic subjects.…”
Section: Discussionmentioning
confidence: 99%
“…In order to complete evaluation of the colon, radiological examinations can be performed such as double contrast barium enema (DCBE) [5] and computed tomography colonography (CTC). In particular, several studies have shown that CTC is a valuable tool to evaluate the proximal colon after incomplete colonoscopy [6][7][8][9][10] , and the American Gastroenterologists Association (AGA) recognized that CTC is indicated for adults with failed colonoscopy [11] . We report the results of CTC systematically performed in subjects with positive FOBT and incomplete colonoscopy in the context of a population-based screening programme for CRC with FOBT.…”
surgery for colonic masses of indeterminate nature. Four subjects refused further examinations. CTC correctly identified 2 colonic masses and 20 polyps. PPV for masses or polyps greater than 9 mm was of 87.5%. Per-lesion and per-segment PPV were, respectively, 83.3% and 83.3% for polyps greater or equal to 10 mm, and 77.8% and 85.7% for polyps of 6-9 mm. CONCLUSION: In the context of a screening program for CRC based on FOBT, CTC shows high per-segment and per-lesion PPV for colonic masses and polyps greater than 9 mm. Therefore, CTC has the potential to become a useful technique for evaluation of the non visualized part of the colon after incomplete colonoscopy.
“…Previous studies on CTC after incomplete colonoscopy have been conducted [6][7][8][9][10] . These studies were inhomogeneous regarding the patients' selection, because they included asymptomatic as well as symptomatic subjects.…”
Section: Discussionmentioning
confidence: 99%
“…In order to complete evaluation of the colon, radiological examinations can be performed such as double contrast barium enema (DCBE) [5] and computed tomography colonography (CTC). In particular, several studies have shown that CTC is a valuable tool to evaluate the proximal colon after incomplete colonoscopy [6][7][8][9][10] , and the American Gastroenterologists Association (AGA) recognized that CTC is indicated for adults with failed colonoscopy [11] . We report the results of CTC systematically performed in subjects with positive FOBT and incomplete colonoscopy in the context of a population-based screening programme for CRC with FOBT.…”
surgery for colonic masses of indeterminate nature. Four subjects refused further examinations. CTC correctly identified 2 colonic masses and 20 polyps. PPV for masses or polyps greater than 9 mm was of 87.5%. Per-lesion and per-segment PPV were, respectively, 83.3% and 83.3% for polyps greater or equal to 10 mm, and 77.8% and 85.7% for polyps of 6-9 mm. CONCLUSION: In the context of a screening program for CRC based on FOBT, CTC shows high per-segment and per-lesion PPV for colonic masses and polyps greater than 9 mm. Therefore, CTC has the potential to become a useful technique for evaluation of the non visualized part of the colon after incomplete colonoscopy.
“…Alternatively radiological imaging (e.g. CT colonography or barium enema) can be applied when endoscopy is technically not feasible or tumour stenosis does not allow complete colonoscopy [20,21]. In these cases colonoscopy should be performed 3-6 months after surgery.…”
Background The laparoscopic approach is increasingly applied in colorectal surgery. Although laparoscopic surgery in colon cancer has been proved to be safe and feasible with equivalent long-term oncological outcome compared to open surgery, safety and long-term oncological outcome of laparoscopic surgery for rectal cancer remain controversial. Laparoscopic rectal cancer surgery might be efficacious, but indications and limitations are not clearly defined. Therefore, the European Association for Endoscopic Surgery (EAES) has developed this clinical practice guideline. Methods An international expert panel was invited to appraise the current literature and to develop evidence-based recommendations. The expert panel constituted for a consensus development conference in May 2010. Thereafter, the recommendations were presented at the annual congress of the EAES in Geneva in June 2010 in a plenary session. A second consensus process (Delphi process) of the recommendations with the explanatory text was necessary due to the changes after the consensus conference. Results Laparoscopic surgery for extraperitoneal (midand low-) rectal cancer is feasible and widely accepted. The laparoscopic approach must offer the same quality of surgical specimen as in open surgery. Short-term outcomes such as bowel function, surgical-site infections, pain and hospital stay are slightly improved with the laparoscopic approach. Laparoscopic resection of rectal cancer is not
“…Several previous articles address large polyps and so-called masses, with this later group not clearly defined. Zalis et al [10] define them as lesions of 30 mm and larger, while Copel et al [11] and Kiraly et al [12] define them as lesions of 20 mm and larger. However, this is a conservative viewpoint with respect to the presence of malignancy (carcinoma) within the lesion and the chance of developing malignancy in the future (advanced adenoma).…”
Abstract-Computerized tomographic colonography is a minimally invasive technique for the detection of colorectal polyps and carcinoma. Computer-aided diagnosis (CAD) schemes are designed to help radiologists locating colorectal lesions in an efficient and accurate manner. Large lesions are often initially detected as multiple small objects, due to which such lesions may be missed or misclassified by CAD systems. We propose a novel method for automated detection and segmentation of all large lesions, i.e., large polyps as well as carcinoma. Our detection algorithm is incorporated in a classical CAD system. Candidate detection comprises preselection based on a local measure for protrusion and clustering based on geodesic distance. The generated clusters are further segmented and analyzed. The segmentation algorithm is a thresholding operation in which the threshold is adaptively selected. The segmentation provides a size measurement that is used to compute the likelihood of a cluster to be a large lesion. The large lesion detection algorithm was evaluated on data from 35 patients having 41 large lesions (19 of which malignant) confirmed by optical colonoscopy. At five false positive (FP) per scan, the classical system achieved a sensitivity of 78%, while the system augmented with the large lesion detector achieved 83% sensitivity. For malignant lesions, the performance at five FP/scan was increased from 79% to 95%. The good results on malignant lesions demonstrate that the proposed algorithm may provide relevant additional information for the clinical decision process.
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