CT-based patient modeling for head and neck hyperthermia treatment planning: Manual versus automatic normal-tissue-segmentation

Local hyperthermia combined with radiotherapy and-/or chemotherapy: Recent advances and promises for the future

“…Using the image data, a full 3D patient model is created by manual, semi-automatic or automatic segmentation of the different tissue types. Often, only muscle, fat, bone and internal air are distinguished, but recently atlas-based approaches in which organs are discriminated have been reported [85][86][87]. In addition, the target volume is delineated, which can comprise the clinical target volume (CTV) or only the gross tumor volume (GTV).…”

Deep hyperthermia with the HYPERcollar system combined with irradiation for advanced head and neck carcinoma – a feasibility study

“…Treatment planning was applied for each patient to derive the settings per antenna (RF-power-weighting, phase-difference) leading to an optimum heat focusing at the target region. A full 3D patient model was generated based on the planning CT for radiotherapy and comprised of exterior, fat, muscle, bone, cartilage, white matter and grey matter [20][21][22]. This 3D model was used for an electromagnetic simulation per antenna.…”

“…The HYPERcollar was placed around the target volume and the waterbolus was filled with deionized water. This water was circulated at a temperature of [20][21][22][23][24][25][26][27][28][29][30] C, depending on target depth. Pre-optimized RFpower and phase settings were applied and RF-power was gradually increased until target temperature or hotspots were reached.…”

MRI integration into treatment planning of head and neck tumors: Can patient immobilization be avoided?

“…The clinical impact of the alignment differences on RTP and HTP can be evaluated by considering the studies [27,4]. Voet et al [27] reported that a small contour distance between different planning target volumes (<1 mm) led to a relevant underdosage (up to 11 Gy).…”

“…The most common imaging modality used for this application is computed tomography (CT) [1][2][3][4] because of its geometrical accuracy and, for RTP, the direct availability of electron density information. However, the superior soft-tissue contrast of magnetic resonance (MR) images with respect to CT has been shown to improve delineation accuracy with which target and normal tissues can be delineated [5][6][7][8].…”