CT- and US-guided biopsy of the pancreas.

Brandt, Kathleen R.; Charboneau, J. William; Stephens, David H.; Welch, Timothy J.; Goellner, John R.

doi:10.1148/radiology.187.1.8451443

Cited by 210 publications

(91 citation statements)

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“…In many of these clinical scenarios, patients may un dergo percutaneous biopsy. The accuracy of biopsy for the diagnosis of cancer versus chronic pancreatitis varies, ranging from 45% to 94% [16,17].As a result, manypa tientsmay proceedto laparotomydespitethe associated costandmorbidity.…”

Section: Discussionmentioning

confidence: 99%

Diagnosis of pancreatic carcinoma: role of FDG PET.

Keogan

Tyler

Clark

et al. 1998

American Journal of Roentgenology

103

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Section: Discussionmentioning

confidence: 99%

Diagnosis of pancreatic carcinoma: role of FDG PET.

Keogan

Tyler

Clark

et al. 1998

American Journal of Roentgenology

103

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“…Whereas FNA only provides cells largely disrupted from their original arrangement, larger-caliber cutting needles allow for core biopsy specimens (11)(12)(13)(14)(15)(16)(17)(18). These specimens have been obtained by several routes (percutaneous, intraluminal and surgical) (16)(17)(18)(19)(20)(21)(22), and safety and accuracy of cutting biopsy have been previously demonstrated (16,(22)(23)(24).…”

Section: Introductionmentioning

confidence: 99%

Evaluation of the adequacy and diagnostic accuracy of the histology samples obtained with a newly designed 19-gauge EUS histology needle

Iglesias‐García

Abdulkader

Lariño‐Noia

et al. 2014

Rev. esp. enferm. dig.

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Background: Endoscopic ultrasound (EUS)-guided fine needle aspiration (FNA) is an accurate technique for sampling intraintestinal and extraintestinal lesions. However, cytology possesses certain limitations, which may be overcome if histological specimens are provided to the pathologist.Aim: The aim of the study was to evaluate the accuracy of a newly developed 19G histology needle.Methods: Retrospective analysis of a prospectively collected data base including patients who underwent EUS-guided biopsy with the 19G ProCore TM histology needle for the evaluation of intraintestinal or extraintestinal lesions. Samples were obtained after one needle pass, recovered into ThinPrep ® and processed for histological analysis. Results were compared to the gold standard of surgical histopathology, or global pathological, clinical and radiological assessment, and follow-up in non-operated cases. Results are shown as mean ± SD. Percentage of optimal samples for histological evaluation and the overall diagnostic accuracy were evaluated.Results: 87 patients (mean age 62.9 years, range 25-88 years, 36 woman) were included. Lesions mean size was 41.6 ± 21.3 mm. 66 lesions (75.9 %) were considered as malignant and 21 (24.1 %) as benign. EUS-guided biopsy was feasible in all cases (100 %). Sample quality was adequate for histological assessment in 82 lesions (94.2 %). In the remaining cases the sample was adequate for cell-block evaluation. Sensitivity, specificity, PPV, NPV, and overall accuracy for malignancy were 93.4 %, 100 %, 100 %, 84 %, and 95.4 %, respectively. There were no complications related to the procedure. Conclusion:The EUS-guided biopsy with the 19G histology needle provides with an optimal core sample for histological evaluation allowing a high histopathologic diagnostic accuracy.

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“…In patients suffering from metastatic disease every effort is made to obtain a pathological diagnosis with percutaneous US-guided FNA, performing endoscopic palliation in patients with obstructive jaundice. In the vast majority of patients this approach can be considered the gold standard with the accuracy of percutaneous diagnostic procedures varying in the literature from 83 to 94% [24, 25]. …”

Section: Discussionmentioning

confidence: 99%

The Role of Laparoscopy in Advanced Pancreatic Cancer Diagnosis

et al. 2007

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Background/Aims: Histological diagnosis between ductal and endocrine carcinoma is imperative in patients with advanced and unresectable pancreatic malignancies because of the different treatment modalities and prognoses. Whenever percutaneous and endoscopic ultrasound-guided pancreatic fine needle aspiration (FNA) fails to obtain a diagnostic specimen, a laparoscopic approach may be employed. Methods: Between October 2002 and July 2004, 19 patients with demonstrated unresectable pancreatic cancer underwent laparoscopy to obtain a cytohistological diagnosis. Results: The mean operative time was 83 min. Laparoscopy showed the presence of liver metastases in 15 patients that were correctly diagnosed by preoperative imaging in only 8 cases (53%). Overall 5 pancreatic FNA and 16 liver and peritoneal biopsies were obtained. In 1 patient the procedure was abandoned due to hypercapnia. In 16 patients (84%) a cytohistological diagnosis was obtained. There were no mortalities. Conclusions: Laparoscopic biopsy of advanced unresectable pancreatic cancer is a feasible, safe and reliable procedure to obtain a cytohistological diagnosis whenever ultrasound-guided FNA fails.

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CT- and US-guided biopsy of the pancreas.

Cited by 210 publications

References 0 publications

Diagnosis of pancreatic carcinoma: role of FDG PET.

Diagnosis of pancreatic carcinoma: role of FDG PET.

Evaluation of the adequacy and diagnostic accuracy of the histology samples obtained with a newly designed 19-gauge EUS histology needle

The Role of Laparoscopy in Advanced Pancreatic Cancer Diagnosis

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