CT and MRI of Uterine Sarcomas and Their Mimickers

Rha, Sung Eun; Byun, Jae Young; Jung, Seung Eun; Lee, Soo Lim; Cho, Song Mee; Hwang, Seong Su; Lee, Hae Giu; Namkoong, Sung-Eun; Lee, Jae Mun

doi:10.2214/ajr.181.5.1811369

Cited by 126 publications

(62 citation statements)

References 8 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…ESS more frequently appears as polypoid endometrial mass, with low signal on T1-weighted images and heterogeneously increased high T2 signal (3,11,15). It typically shows myometrial involvement, either sharply demarcated or in a more diffuse and destructive manner (the latter is far more common with UES) (Fig.…”

Section: Mri Featuresmentioning

confidence: 99%

“…In these cases, intramyometrial ESS can be differentiated based on their rapid and invasive growth, lower degree of enhancement, lymphatic and vascular invasion, higher incidence of necrosis, peripheral hypointense rim on T2-weighted images, and enhanced marginal irregularity (3,11,15,18).…”

Section: Mri Featuresmentioning

confidence: 99%

“…UES tends to occur in an older age group, when compared to ESS, with a mean age of 61 years at the time of diagnosis (2,11). Signs and symptoms resemble those of leiomyosarcoma and include vaginal bleeding, palpable pelvic mass, and pelvic pain (16).…”

Section: Undifferentiated Endometrial Sarcoma Clinical Featuresmentioning

confidence: 99%

“…5a). The latter is attributable to the high frequency of hemorrhage and necrosis within the tumor (11,14,17). UES tends to infiltrate the myometrium in a more destructive and extensive manner than ESS, due to marked vascular and lymphatic invasion (3, 11).…”

Section: Mri Featuresmentioning

confidence: 99%

See 3 more Smart Citations

Uterine sarcomas: clinical presentation and MRI features

Santos

Cunha²

2015

Diagn Interv Radiol

155

138

View full text Add to dashboard Cite

Uterine sarcomas are a rare heterogeneous group of tumors of mesenchymal origin, accounting for approximately 8% of uterine malignancies. They comprise leiomyosarcoma, endometrial stromal sarcoma, undifferentiated endometrial sarcoma, and adenosarcoma. Compared with the more common endometrial carcinomas, uterine sarcomas behave more aggressively and are associated with a poorer prognosis. Due to their distinct clinical and biological behavior, the International Federation of Gynecology and Obstetrics introduced a new staging system for uterine sarcomas in 2009, categorizing uterine carcinosarcoma as a variant of endometrial carcinoma, rather than a pure sarcoma. Magnetic resonance imaging (MRI) has a developing role in the assessment of these malignancies. Features such as tumor localization, irregular or nodular margins, necrosis, rapid growth, intense contrast enhancement, and restriction at diffusion-weighted imaging can suggest the diagnosis and help differentiate from more common leiomyomas and endometrial carcinoma. MRI is therefore extremely useful in preoperative detection and staging and, consequently, in determination of appropriate management. This pictorial review aims to discuss the clinical features of uterine sarcomas, as well as their most common appearances and distinct characteristics in MRI.

show abstract

Section: Mri Featuresmentioning

confidence: 99%

Section: Mri Featuresmentioning

confidence: 99%

Section: Undifferentiated Endometrial Sarcoma Clinical Featuresmentioning

confidence: 99%

Section: Mri Featuresmentioning

confidence: 99%

See 2 more Smart Citations

Uterine sarcomas: clinical presentation and MRI features

Santos

Cunha²

2015

Diagn Interv Radiol

155

138

View full text Add to dashboard Cite

show abstract

“…The MRI findings in our patient also documented this important criterion. Post contrast imaging of the masses generally have low signal intensity when benign, and high signal intensity when malignant [5] [6]. As seen from the literature, it is without question that strong objective criterion for accurately predicting uterine sarcomas has yet to be determined.…”

Section: Discussionmentioning

confidence: 99%

Revisiting Imaging and Pathology of Malignant Appearing Uterine Smooth Muscle Tumors: A Mistaken Identity of Leiomyosarcoma on MRI

Juhl¹,

Knuttinen²,

Kothari³

et al. 2014

OJRad

View full text Add to dashboard Cite

Uterine leiomyoma is a relatively common condition occurring in a majority of African American and Caucasian women by age 50. Magnetic resonance imaging of the pelvis with contrast is the modality of choice when evaluating uterine tumors. We report a case of a patient with a four-day history of intra-menstrual vaginal bleeding who underwent magnetic resonance imaging of the pelvis that suggested the tumor was a leiomyosarcoma, the malignant counterpart of leiomyoma. Therefore, the patient underwent pre-operative uterine artery embolization to decrease blood loss with exploratory laparotomy, resection of pelvic mass and dilation and curettage. Pathologic evaluation of the mass returned a diagnosis of leiomyoma. Magnetic resonance imaging evaluation of leiomyomata remains difficult. Further development of imaging parameters could improve diagnosis of benign uterine fibroids.

show abstract

Uterine Leiomyosarcoma

Carmen¹

2014

Uncommon Gynecologic Cancers

View full text Add to dashboard Cite

CT and MRI of Uterine Sarcomas and Their Mimickers

Cited by 126 publications

References 8 publications

Uterine sarcomas: clinical presentation and MRI features

Uterine sarcomas: clinical presentation and MRI features

Revisiting Imaging and Pathology of Malignant Appearing Uterine Smooth Muscle Tumors: A Mistaken Identity of Leiomyosarcoma on MRI

Uterine Leiomyosarcoma

Contact Info

Product

Resources

About