CT and angiography of peliosis hepatis

Tsukamoto, Yoshihiro; Nakata, Hiroaki; Kimoto, Tsunenobu; Noda, Takuo; Kuroda, Y; Haratake, Joji

doi:10.2214/ajr.142.3.539

Cited by 29 publications

(13 citation statements)

References 3 publications

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“…Peliosis hepatitis is a rare condition characterized by multiple small blood-filled spaces in the liver parenchyma. CT scan shows oval-shaped lesions that are homogeneously enhanced after intravenous injection of contrast agents (19). The liver specimen obtained after her death revealed that these lesions correspond to areas of hepatic necrosis, as previously pointed out in some cases.…”

Section: Discussionsupporting

confidence: 66%

Fulminant Hepatic Failure Caused by Adenovirus Infection Mimicking Peliosis Hepatitis on Abdominal Computed Tomography Images after Allogeneic Hematopoietic Stem Cell Transplantation

et al. 2012

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Disseminated adenovirus disease after allogeneic hematopoietic stem cell transplantation (HSCT) is lethal in most cases, especially when it develops as fulminant hepatic failure. We encountered a patient who developed fulminant hepatic failure caused by adenovirus infection. She did not show manifestations of graftversus-host disease and the results of serum tests for viral infection were all negative. Abdominal computed tomography (CT) findings were consistent with peliosis hepatitis. She died of fulminant hepatic failure, however, and pathological examinations of the liver specimen obtained after her death revealed adenovirus infection. In this report, we review the clinical characteristics and imaging findings of fulminant hepatic failure caused by adenovirus infection.

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Section: Discussionsupporting

confidence: 66%

Fulminant Hepatic Failure Caused by Adenovirus Infection Mimicking Peliosis Hepatitis on Abdominal Computed Tomography Images after Allogeneic Hematopoietic Stem Cell Transplantation

et al. 2012

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“…Yanoff and Rawson [5] described two types of peliosis hepatis: parenchymal and phlebestatic. In the former, the blood-filled spaces have no endothelial lining and are usually associated with hemorrhagic parenchymal necrosis; in the latter, the spaces are lined with endothelium and are based on aneurysmal dilatation of the central vein [6]. Pathological findings in our patient were characteristic of the first type: histological examination of the liver biopsy showed foci of hemorrhagic necrosis and multiple blood-filled spaces in the parenchyma with no endothelial lining.…”

Section: Discussionmentioning

confidence: 58%

Hemorrhagic necrosis due to peliosis hepatis: imaging findings and pathological correlation

et al. 1999

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Peliosis hepatis is an uncommon liver condition characterized by blood-filled cavities. We report the CT, angiographic and MR features of a case of peliosis hepatis with no obvious etiology and spontaneously regressing hemorrhagic necrosis. Helical CT showed multiple peripheral low-density regions with foci of spontaneous high density suggesting the presence of blood component. On MR imaging, the multiple peripheral lesions were hypointense on T1-weighted and hyperdense on T2-weighted images, with bright foci on all sequences suggesting subacute blood. Angiography showed no evidence of tumor or vascular malformation; multiple nodular vascular lesions filling in the parenchymal phase and persisting in the venous phase suggested blood-filled cavities. Pathological examination showed blood-filled spaces with no endothelial lining, characteristic of the parenchymal type of peliosis. Knowledge of the imaging features of hemorrhagic necrosis due to peliosis hepatis is important since it can be responsive to antibiotic therapy. Furthermore, differentiating hemorrhagic necrosis from hepatic abscess avoids dangerous and sometimes fatal percutaneous drainage.

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“…Angiographically, peliotic lesions of various sizes have been described as showing an accumulation of contrast agent detected late in the arterial phase and becoming more prominent in the parenchymal and venous phases. [15][16][17] Ultrasound examination may show areas of heterogenous echogenicity, and CT scanning frequently reveals patchy low-density areas that may or may not enhance with contrast medium. 18 MR findings seem normal, or show lesions with slightly increased signals on T1-and T2-weighted images.…”

Section: Discussionmentioning

confidence: 99%

Peliosis hepatis during postpartum period: successful embolization of hepatic artery

Omori

Asahi

Irinoda

et al. 2004

Journal of Gastroenterology

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Peliosis hepatis is a rare disorder characterized by the presence of blood-filled spaces in the liver, and it usually has a chronic presentation pattern. It has been reported mainly in adult patients in association with various pharmacological agents and infections. The present report concerns a postpartum patient in whom peliosis hepatis initially presented as active intraperitoneal hemorrhage from peliotic liver lesions, with no obvious etiology. We report here a 31-year-old woman who developed symptomatic peliosis hepatis and underwent superselective hepatic artery embolization, with control of the bleeding. We also present the sonographic, computed tomographic, and magnetic resonance images and laparoscopic findings. The patient recovered well and was discharged without any complaints. The pathogenesis in this patient remains unclear, but it is suggested that in her case estrogens and progesterone could not have been responsible for the development of peliosis hepatis.

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CT and angiography of peliosis hepatis

Cited by 29 publications

References 3 publications

Fulminant Hepatic Failure Caused by Adenovirus Infection Mimicking Peliosis Hepatitis on Abdominal Computed Tomography Images after Allogeneic Hematopoietic Stem Cell Transplantation

Fulminant Hepatic Failure Caused by Adenovirus Infection Mimicking Peliosis Hepatitis on Abdominal Computed Tomography Images after Allogeneic Hematopoietic Stem Cell Transplantation

Hemorrhagic necrosis due to peliosis hepatis: imaging findings and pathological correlation

Peliosis hepatis during postpartum period: successful embolization of hepatic artery

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