Crystallographic characterization of irradiated U-10Zr and U-10Zr-5Ce metallic fuels

Pd-Catalyzed Three-Component Coupling of Cyclopropenones via Sequential C–C Bond Activation and Allylation

“…Inspired by this, we envisioned that the nucleophilic attack by carboxylic acids on VECs might provide a stereocontrolled method for the construction of multisubstituted allylic esters with a naked allyl alcohol moiety. Such complex structures are fundamental building blocks in many bioactive natural products and pharmaceutically relevant compounds, such as 19-nor-neo-clerodane (Figure 1A), 7 cytotoxic vernolide (Figure 1B), 8 sesquiterpene lactone (Figure 1C), 9 and juniferol ester (Figure 1D). 10 Given the presence of α,β-unsaturated carbonyl structures in these important molecules, we recently wondered whether it might be possible to combine the ring-opening of cyclopropenones with the decarboxylation of vinylethylene carbonates to access a vast array of synthetically valuable scaffolds in domino reactions.…”