Crystallization of mixtures of local anesthetics with and without select adjuvants: a semiquantitative light microscopy analysis
Elisabeth Hoerner,
Ottokar Stundner,
Anna Seisl
et al.
Abstract:IntroductionInjecting mixtures of local anesthetics with or without adjuvants is a common practise in regional and particularly obstetric anesthesia to decrease block onset time and/or augment epidural analgesia for cesarean section. While evidence on the efficacy of this practise is equivocal, little is known about its safety in terms of the pharmacologic compatibility of local anesthetics.MethodsWe assessed the grade of crystallization in individual mixtures of seven local anesthetics (bupivacaine, ropivacai… Show more
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