Abstract:A rigid bis(urea) molecular cleft (BU1) based on the cis diastereomer of a rigid isophorone-derived spacer forms solid-state inclusion complexes with a range of small molecular guests. Larger guests can be accommodated by a shift in orientation to open up crystalline channels while retaining the same overall hydrogen-bonded topology. The introduction of molecular flexibility to give BU2, which possesses a methylene spacer, destroys the host−guest complexation behavior and restores the more conventional urea α-… Show more
Set email alert for when this publication receives citations?
scite is a Brooklyn-based organization that helps researchers better discover and understand research articles through Smart Citations–citations that display the context of the citation and describe whether the article provides supporting or contrasting evidence. scite is used by students and researchers from around the world and is funded in part by the National Science Foundation and the National Institute on Drug Abuse of the National Institutes of Health.