Abstract:Malaria is an infectious disease caused by the parasite Plasmodium falciparum invading red blood cells. Toxic free heme released by the parasitic destruction of hemoglobin is detoxified by conversion to malaria pigment. The µ-oxo TPP and OEP heme complexes have been studied as malaria pigment model systems [1]. The current study focuses on structure correlation of these and [Fe(PPIX)] 2 (µ-O) in an effort to better understand the relationship between the spectra of malaria pigment and the µ-oxo heme complexes.… Show more
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