Crystal structure of methyl (Z)-2-(5-fluoro-2-oxoindolin-3-ylidene)hydrazine-1-carbodithioate, C₁₀H₈FN₃OS₂

Abstract

C 10 H 8 FN 3 OS 2 , monoclinic, P2 1 /c (no. 14), a = 6.2909(2) Å, CCDC no.: 1557525The crystal structure is shown in the figure. Tables 1 and 2 contain details on crystal structure and measurement conditions and a list of the atoms including atomic coordinates and displacement parameters. Source of materialThe title compound was obtained via condensation of 5-fluoroindoline-2,3-dione (0.3 g, 2 mmol) with methyl hydrazinecarbodithioate (0.2 g, 2 mmol) in 8 mL methanol at room temperature for 12 h. The mixture was isolated by column chromatography on silica gel with dichloromethane/methanol = 98:2 (v/v) as eluent to give the title compound methyl (Z)-2-(5-fluoro-2-oxoindolin-3-ylidene)hydrazine-1-carbodithioate (yield 65%; m.p.

Synthesis and crystal structure of (±)-Ethyl 5′-(difluoromethyl)-2-oxo-4′,5′-dihydrospiro[indoline-3,3′-pyrazole]-4′-carboxylate, C14H13F2N3O3

“…The 4, 5-dihydro-3H-pyrazole ring adopts an envelope conformation with C9 atom deviating by 0.3474(3) Å from the plane formed by C1, C10, N1 and N2 for Mole1, C9A atom deviats by 0.3816(2) Å from the plane formed by C1A, C10A, N1A and N2A for Mole2 [15]. The bond lengths and angles of indolin-2-one and 4,5-dihydro-1H-pyrazole ring are similar to those found in literature [16][17][18]. The indolin-2-one ring and 4,5-dihydro-3Hpyrazole ring form spiro structural feature through their third atom (C1).…”