Crystal structure of (S)-2-[(3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-N-methoxy-N-methylpropanamide (Fernholz Weinreb amide)

Viktorsson, Elvar Örn; Åstrand, Ove Alexander Høgmoen; Haseeb, Rasha Sabah; Görbitz, Carl Henrik; Rongved, Pål

doi:10.1107/s2056989015001747

Acta Cryst E

2015

DOI: 10.1107/s2056989015001747

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Crystal structure of (S)-2-[(3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-N-methoxy-N-methylpropanamide (Fernholz Weinreb amide)

Elvar Örn Viktorsson

Ove Alexander Høgmoen Åstrand

Rasha Sabah Haseeb

et al.

Abstract: In research towards new antagonists against the Liver X receptor, the important intermediate Fernholz acid Weinreb amide has been synthesized and characterized.

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Crystal structure of (S)-2-[(3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-N-methoxy-N-methylpropanamide (Fernholz Weinreb amide)

Abstract: In research towards new antagonists against the Liver X receptor, the important intermediate Fernholz acid Weinreb amide has been synthesized and characterized.

Cited by 1 publication

References 21 publications

Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations

Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations

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Crystal structure of (S)-2-[(3S,8S,9S,10R,13S,14S,17R)-3-hydroxy-10,13-dimethyl-2,3,4,7,8,9,10,11,12,13,14,15,16,17-tetradecahydro-1H-cyclopenta[a]phenanthren-17-yl]-N-methoxy-N-methylpropanamide (Fernholz Weinreb amide)

Abstract: In research towards new antagonists against the Liver X receptor, the important inter­mediate Fernholz acid Weinreb amide has been synthesized and characterized.

Cited by 1 publication

References 21 publications

Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations

Regulation of liver X receptor target genes by 22-functionalized oxysterols. Synthesis, in silico and in vitro evaluations

Contact Info

Product

Resources

About

Abstract: In research towards new antagonists against the Liver X receptor, the important intermediate Fernholz acid Weinreb amide has been synthesized and characterized.