Crystal structure of G-1F mutant of Ssp DnaB Mini-Intein variant M86

The biological and functional significance of selected Critical Assessment of Techniques for Protein Structure Prediction 14 (CASP14) targets are described by the authors of the structures. The authors highlight the most relevant features of the target proteins and discuss how well these features were reproduced in the respective submitted predictions. The overall ability to predict three-dimensional structures of proteins has improved remarkably in CASP14, and many difficult targets were modeled with impressive accuracy. For the first time in the history of CASP, the experimentalists not only highlighted that computational models can accurately reproduce the most critical structural features observed in their targets, but also envisaged that models could serve as a guidance for further studies of biologicallyrelevant properties of proteins.

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Target highlights in CASP14: Analysis of models by structure providers

Alexander

Lepore

Kryshtafovych

et al. 2021

Proteins

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Chung

Krahn

Crnković

et al. 2022

Journal of Molecular Biology

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Clark

Sievers

Debelouchina

2022

Journal of Magnetic Resonance Open

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Crystal structure of G-1F mutant of Ssp DnaB Mini-Intein variant M86

Cited by 7 publications

References 48 publications

Target highlights in CASP14: Analysis of models by structure providers

Target highlights in CASP14: Analysis of models by structure providers

Intein-based Design Expands Diversity of Selenocysteine Reporters

A Chemical Biology Primer for NMR Spectroscopists

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