1991
DOI: 10.1016/0022-2836(91)90192-9
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Crystal structure of cholesterol oxidase from Brevibacterium sterolicum refined at 1.8 Å resolution

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Cited by 188 publications
(179 citation statements)
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“…Members of this subfamily include choline dehydrogenase {Eseherichia coli), glucose dehydrogenase (Drosophila melanogasterL alcohol dehydrogenase (Pseudomonas oleovoraHs), nlethanol oxidase (Han.vemtla poO'morpha and Pichia pastoris), glucose oxidase (Aspergillu,s ni~er) and cholesterol oxidase from Brevihacterium slerolicum. To date, three-dimensional structures have been reported l\~r the two latter enzymes [30,31]. The GMC oxidoreductases all carry FAD as a col'actor, but in contrast to CDH, they do not contain a heine group.…”
Section: Resultsmentioning
confidence: 99%
“…Members of this subfamily include choline dehydrogenase {Eseherichia coli), glucose dehydrogenase (Drosophila melanogasterL alcohol dehydrogenase (Pseudomonas oleovoraHs), nlethanol oxidase (Han.vemtla poO'morpha and Pichia pastoris), glucose oxidase (Aspergillu,s ni~er) and cholesterol oxidase from Brevihacterium slerolicum. To date, three-dimensional structures have been reported l\~r the two latter enzymes [30,31]. The GMC oxidoreductases all carry FAD as a col'actor, but in contrast to CDH, they do not contain a heine group.…”
Section: Resultsmentioning
confidence: 99%
“…The 3D structures of GOX and DAOX show topological similarities with regard to the FAD-binding pocket [3,5,19]. Also AO, which displays sequence homology with GOX (approximately 25% identity), may have a similar structure [14].…”
Section: Discussionmentioning
confidence: 97%
“…Lactate dehydrogenase (LDH), 61dh (Abad-Zapatero et al, 1987); alcohol dehydrogenase (ADH), 8adh (Colanna-Cesari et al, 1986); malate dehydrogenase (MDH), 4mdh (Birktoft et al, 1989); glyceraldehyde-3-phosphate dehydrogenase (GAH), lgdl (Skarzynski et al, 1987); glutathione reductase (GRS), 3grs (Karplus & Schulz, 1987); hydroxybenzoate hydrolase (PHH), 1 phh (Schreuder et al, 1989); ferredoxin NADP reductase (FNR), lfnr (Karplus et al, 1991); phthalate dioxygenase reductase (PDR), 2pia (Correll et al, 1992); adenylate kinase (ADK), 3adk (Dreusicke et al, 1988); guanylate kinase (GKY), lgky (Stehle & Schulz, 1990); ras p21 (P21), 5p21 (Pai et al, 1989); recA (REC), 2reb (Story & Steitz, 1992); phosphofructokinase (PFK), lpfk (Skirakihara & Evans, 1988) 4fxn (Smith et al, 1977); thioredoxin reductase (TRB), ltrb (Kuriyan et al, 1991b); cholesterol reductase (COX), lcox (Vrielink et al, 1991); 6-phosphogluconate dehydrogenase (PGD), lpgd (Adams et al, 1991); tryptophan synthetase (WSY), lwsy (Hyde et al, 1988); UDP-galactose 4-epimerase (UDP), ludp (Bauer et al, 1992); trimethylamine dehydrogenase (TMD), 1 tmd (Lim et al, 1988); trypanothione reductase (TPR), 2tpr (Kuriyan et al, 1991a); NADH peroxidase (NPX), lnpx (Stehle et al, 1991).…”
Section: Methodsmentioning
confidence: 99%