Crystal structure of 4-(1-phenylimidazo[1,5-a]pyridin-3-yl)benzoic acid (C₂₀H₁₄N₂O₂)

Abstract

C20H14N2O2, monoclinic, C2/c (no. 15), a = 17.8410(5) Å, b = 15.3081(4) Å, c = 11.3881(3) Å, β = 104.280(1)°, V = 3014.12(14) Å3, Z = 8, Rgt(F) = 0.0364, wRref(F2) = 0.0997, T = 100(2) K.

Synthesis and Therapeutic Potential of selected Schiff Bases: In vitro Antibacterial, Antioxidant, Antidiabetic, and Computational Studies

“…Hence, our interest in studying the biological potential of L 1 – L 3 . Schiff bases ( E )‐ N ‐(4‐bromophenyl)‐1‐(2‐nitrophenyl)methanimine ( L 1 ), ( E )‐2‐((mesitylimino)methyl)phenol ( L 2 ) and ( E )‐ N ‐(4‐bromophenyl)‐1‐(pyridin‐2‐yl)methanimine ( L 3 ) were synthesized using modified literature procedures [17–19] . 2, 4, 6‐trimethylaniline (5 mmol, ca .…”

“…were synthesized using modified literature procedures. [17][18][19] 2, 4, 6trimethylaniline (5 mmol, ca. 0.70 mL) or 4-bromoaniline (5 mmol, 0.86 g) in anhydrous ethanol (10 mL) was added to a hot ethanolic solution of 2-nitrobenzaldehyde (5 mmol, 0.76 g), 2-pyridinecarboxaldehyde (5 mmol, ca.…”

Mononuclear discrete Ag(I) complexes of aryl substituted (E)-N-phenyl-1-(pyridin-3-yl)methanimine: In vitro biological activities and interactions with biomolecules

“…Schiff bases (E)-2-((pyridin-3-ylmethylene)amino)phenol (L1), (E)-N-(2-fluorophenyl)-1-(pyridin-3-yl)methanimine (L2) and (E)-1-(pyridin-3-yl)-N-(p-tolyl)methanimine (L3) were synthesized using a slightly modified literature procedures. 3,27,28 In the presence of glacial acetic acid, a hot solution of 3-pyridinecarboxaldehyde (1 mmol,~0.1 mL) in anhydrous ethanol (10 mL) was added to a hot solution of 2-aminophenol (1 mmol, 0.1 g), 1-amino-2-fluorobenzene (1 mmol, 0.1 mL), and 4-methylaniline (1 mmol, 0.11 g) respectively. The resultant reaction was refluxed at 80 °C for 4 h. Under reduced pressure, L1 and L3 solutions were evaporated to one-third of their original volume, and ether (10 mL) was added to each solution to produce a precipitate.…”