Crystal structure of 2-bromo-4-chloro-6-[(4-chlorophenylimino) methyl]phenol, C13H8BrCl2NO

Abstract

Source of material 3-Bromo-5-chlorosalicylaldehyde(23.5 mg,0.1 mmol)was dissolved in 15 mL methanol, then the solution of 4-chloroaniline (12.8 mg, 0.1 mmol) in 15 mL methanol was added with vigorous stirring. The reaction mixture was refluxed for 1hand cooled at room temperature, then the orange products appeared. The products were filtered off, washed with cold methanol, and finally dried to obtain the title Schiff base (yield 72.3 %). Single crystals suitable for X-ray structure determination were obtained by slowly evaporating the filtrate for about ten days at room temperature. The molecule adopts a trans configuration about C=N, and the whole molecule is nearly coplanar with a dihedral angle of 32.67(1)°between the two aromatic rings. An intramolecular O-H×××Nh ydrogen bond is observed between hydroxyland imine group. Two discrete molecules are held together into ad imer by the intermolecular hydrogen bond C7-H7×××Cl2( -x +1,-y+1,-z+1), thed imersa re linked by C10-H10×××Cl2 interaction (-x+2,-y+1,-z+2)toformachain,the R 4 4 8 ()rings are generated by the combination of two C10-H10×××Cl2 hydrogen bonds. The chains are further linked to generate at wo-dimentional network structure by Br1×××Br1(-x+1,-y+1,-z+1) interactions with d(Br1×××Br1) = 3.837 Å. The hydrogen bonds and halogen-halogen interactions play very important roles in formation, stability and crystallization of the title compound. Experimental details

Characterising Supramolecular Architectures in Crystals Featuring I⋯Br Halogen Bonding: Persistence of X⋯X’ Secondary-Bonding in Their Congeners

“…Nevertheless, if two independent X• • • X' contacts longer than the van der Waals radii are considered (see Table S2 for geometric details), supramolecular tapes are apparent, as shown for 16_I2 in Table S2. No separations less than the van der Waals radii are noted in the crystals of 16_Cl2 [91]. It is noted that long type-II Br• • • Br and Br• • • Cl interactions link molecules into a layer and these are connected into a three-dimensional array via long, type-II Cl• • • Cl contacts.…”