Crystal structure, DFT study, antimicrobial properties and DNA cleavage potential and thermal behavior of some new mercury complexes

Montazerozohori, Morteza; Mohammadi, H.; Masoudiasl, A.; Nasr‐Esfahani, Masoud; Naghiha, Reza; Assoud, Abdeljalil

doi:10.1007/s13738-016-0978-8

Cited by 6 publications

(4 citation statements)

References 33 publications

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“…The bond lengths of Hg−I are 2.6534(7) and 2.6658(7) Å, which are longer than those observed in related complexes. 52,53 Unlike CP 1, each of the two adjacent ligands with opposite helicity in CP 2 is connected by Hg(II) ions to form a 1D heterochiral polymer (-P-Hg-M-) via a self-discrimination process (Figure 3b). In the extended structure, each 1D heterochiral chain is connected to the adjacent chains via π•••π stacking interactions between the benzene and pyridine rings, forming a 2D network parallel to the bc plane (Figure 3c).…”

Section: Materials and Physical Measurementsmentioning

confidence: 99%

1D Coordination Polymers Constructed from Pyridine-2,6-Dicarboxamide Ligands Showing Selective and Recyclable Adsorption toward Methanol Vapor

Tian,

Jiang,

Shen

et al. 2024

Crystal Growth & Design

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Two helical ligands (L 1 and L 2 ) containing a pyridine-2,6-dicarboxamide skeleton were synthesized, and the crystal structures indicated racemic configurations with equal amounts of P- and M-helicity. Eight one-dimensional coordination polymers (CPs), {[ZnL 1 Cl2]·2CH3OH} n (1), [HgL 1 I2] n (2), {[AgL 1 NO3]·CHCl3} n (3), {[Cd(L 1 )2Cl2]·2DMF} n (4), {[Co(L 1 )2Cl2]·2DMF} n (5), {[ZnL 2 I2]·2DMF·H2O} n (6), [HgL 2 Cl2] n (7), and {[Hg2(L 2 )2Br4]·2CH3OH} n (8), were synthesized from the reaction of the two ligands with a series of transition metal ions. The crystal structures showed that the chiral self-assembly process of these ligands resulted in homochiral complexes (CP 1, 3, and 6), heterochiral complexes (CP 2, 4, 5, and 7), or the coexistence of homochiral and heterochiral complexes (CP 8). The gas adsorption/desorption experiments were investigated at room temperature, which showed that all the CPs exhibited good selective adsorption capacities (24.6–62.5 cm3/g) toward methanol vapor over other gas. Furthermore, CP 3, 5, and 6 were selected for the recyclable methanol vapor adsorption experiments, and the results showed that all three CPs can be recycled as good adsorbents for methanol vapor.

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Section: Materials and Physical Measurementsmentioning

confidence: 99%

1D Coordination Polymers Constructed from Pyridine-2,6-Dicarboxamide Ligands Showing Selective and Recyclable Adsorption toward Methanol Vapor

Tian,

Jiang,

Shen

et al. 2024

Crystal Growth & Design

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“…Because of these interesting biological properties of cadmium complexes and according to our previously performed studies on N 2 and N 3 donor Schiff bases, in the present work, we report synthesis of a novel bidentate imidazolidine Schiff base ligand by the condensation of N′ ‐(2‐aminoethyl)‐ethane‐1,2‐diamine and 2‐bromobenzaldehyde to form 4‐coordinated cadmium(II) complexes. The compounds were identified using various spectral techniques, such as Fourier transform infrared (FT‐IR), UV‐visible (Vis), proton and carbon nuclear magnetic resonance ( 1 H and 13 C NMR), and conductivity measurements.…”

Section: Introductionmentioning

confidence: 96%

Some new 4-coordinated nanostructure cadmium imidazolidine Schiff base complexes: Thermal behavior, antimicrobial, and DNA cleavage potential

2017

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In this study, a new series of cadmium halide/pseudohalide complexes with a novel Schiff base ligand containing imidazolidine ring has been successfully synthesized.The structure of the ligand and its complexes was characterized by analysis tools such as Fourier transform infrared, UV-visible, proton and carbon nuclear magnetic resonance spectra, molar conductance, and thermal analysis. Also cadmium bromide and iodide nanostructure complexes have been prepared via sonochemical method. X-ray powder diffraction and scanning electron microscopy techniques confirmed nanostructure sheets for these 2 cadmium complexes. All the newly prepared compounds were screened for their antimicrobial activities, against 4 bacterial and 2 fungal strains using disk diffusion and serial dilution methods. The CdL(N 3 ) 2 and CdLCl 2 complexes showed the best antimicrobial activity as compared with other compounds. Moreover, DNA cleavage potential of all compounds was investigated by agarose gel electrophoresis method. The results showed remarkable ability of some cadmium complexes for DNA cleavage. Furthermore, thermal behaviors of all cadmium complexes were studied in the range of room temperature to 800°C under nitrogen atmosphere. The complexes were thermally decomposed via 2 to 4 steps. Cadmium metal was suggested as final residue at the end of thermal decomposition process.

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“…These compounds from flavonoids make them display antibacterial [23], anti-inflammatory [24], antifungal [25], anticancer [26], and many other pharmacological activities. The chalcone with α, β unsaturated carbonyl group, and chromanone moiety may increase the pharmaceutical efficiency since chromanone has good biological activity such as antioxidant, anti-leishmanial [27][28], antimicrobial [29]. The antivascular activity of chalcones several tubulin-binding agents that inhibit tubulin assemblies, such as colchicine and vincristine, have recently been demonstrated to also disrupt tumor vasculature [29].…”

Section: Introductionmentioning

confidence: 99%

“…The chalcone with α, β unsaturated carbonyl group, and chromanone moiety may increase the pharmaceutical efficiency since chromanone has good biological activity such as antioxidant, anti-leishmanial [27][28], antimicrobial [29]. The antivascular activity of chalcones several tubulin-binding agents that inhibit tubulin assemblies, such as colchicine and vincristine, have recently been demonstrated to also disrupt tumor vasculature [29]. Presumably, these agents are capable of rapidly changing the shape of endothelial cells, thereby disrupting the endothelial cell layer surrounding blood vessels and exposing underlying basement membranes [30].…”

Section: Introductionmentioning

confidence: 99%

Crystal Structure, Hirshfeld Surfaces and Energy Framework Studies of a Biologically Active Compound (3E)-3- (2,4- dimethoxybenzyldene) -2,3-dihydro- 4H-chromen-4-one

Hemalatha

Jonathan

Shirmila

et al. 2021

CSIJ

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A new chalcone derivative (3E)-3-(2,4-dimethoxybenzyldene)-2,3-dihydro-4H-chromen-4-one (DBDB) has been synthesized by following the Claisen-Schmidt condensation reaction method at ambient temperature using the slow evaporation technique. The 3D crystal structure was solved using the single-crystal X-ray diffraction method (XRD). XRD intensity data reveal that the title compound crystallizes in an orthorhombic crystal system with non-centrosymmetric space group P21 21 21. The crystallographic parameters such as bond lengths, bond angles, torsion angles were estimated and are found to be in the normal range and comparable with the literature values. The unit cell packing of the molecules shows that the adjacent molecules are linked via C-H…O hydrogen bonds. Hirshfeld surfaces namely dnorm, electrostatic potential, shape index, and curvedness were analyzed to visualize and to evaluate the weak intermolecular interactions, positive and negative potential regions, C-H…π, and π…π stacking interactions, respectively. The 2D fingerprint plots for the whole and delineated interactions were generated and analyzed to estimate their contributions to the total Hirshfeld surfaces. The pairwise intermolecular interactions were calculated as the sum of four scaled energy components namely electrostatic (Eele), polarization (Epol), dispersion (Edis), and exchange-repulsion (Erep) and graphically represented as energy frameworks. The energy frameworks analysis reveals that the total stabilizing energy is highly influenced by dispersion (Edis) energy than the other components. In-vitro and in-silico investigations have also been performed for the title molecule which discloses the efficacious for use as a drug in inhibiting breast cancer cells without affecting the normal cells.

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Crystal structure, DFT study, antimicrobial properties and DNA cleavage potential and thermal behavior of some new mercury complexes

Cited by 6 publications

References 33 publications

1D Coordination Polymers Constructed from Pyridine-2,6-Dicarboxamide Ligands Showing Selective and Recyclable Adsorption toward Methanol Vapor

1D Coordination Polymers Constructed from Pyridine-2,6-Dicarboxamide Ligands Showing Selective and Recyclable Adsorption toward Methanol Vapor

Some new 4-coordinated nanostructure cadmium imidazolidine Schiff base complexes: Thermal behavior, antimicrobial, and DNA cleavage potential

Crystal Structure, Hirshfeld Surfaces and Energy Framework Studies of a Biologically Active Compound (3E)-3- (2,4- dimethoxybenzyldene) -2,3-dihydro- 4H-chromen-4-one

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