Crystal structure and Hirshfeld surface analysis of ethyl (3E)-5-(4-chlorophenyl)-3-{[(4-chlorophenyl)formamido]imino}-7-methyl-2H,3H,5H-[1,3]thiazolo[3,2-a]pyrimidine-6-carboxylate

Abstract

In the title molecule, C23H20Cl2N4O3S, the thiazole ring is planar while the pyrimidine unit fused to it adopts a screw-boat conformation. In the crystal, thick sheets parallel to the bc plane are formed by N—H...N, C—H...N and C—H...O hydrogen bonds together with π–π interactions between the formamido carbonyl groups and the thiazole rings. Hirshfeld surface analysis indicates that the most important contributions to the crystal packing are from H...H (30.9%), Cl...H/H...Cl (20.7%), C...H/H...C (16.8%) and O...H/H...O (11.4%) interactions.

Effect of Exogenous Application of Gibberellic Acid (GA3) on Seed Size and Fruit Quality of Prickly Pear Cactus (Opuntia ficus-indica)

“…Data are average of a minimum of five fruits per treatment and evaluated statistically by the calculation of averages + standard deviation or ANOVA and mean separation by Duncan’s multiple range tests at the 5% level of significance. This work confirms that there are different applications for bioactive compounds in agriculture and other fields which is reflected in many papers that have been published before. − Also, it is interesting to clarify that the importance of this paper and other agricultural research lies in their significant contribution in solving worldwide concerns, including food security, environmental sustainability, and economic development. − …”

Development and validation of a green RP-HPLC method for detection and quantitation of meropenem trihydrate in the bulk: A comparison with HPTLC method

“…This work confirms the high importance of organic molecules due to their various applications as reported before. [22][23][24][25][26][27]…”

Effect of pH variation and temperature on pesticides sorption characteristics in calcareous soil

“…4,5,6 Sorption has major effects on the physical accessibility of microorganisms to the pollutant and plays a significant role in the pollutant's mobility. 7,8 Acidic herbicides exist as either anions or neutral molecules depending upon whether the soil solution pH is below or above the pKa. Theoretically, anionic, and neutral forms will be present in equal amounts when the pH is equal to the pKa.…”

“…10 One of the main environmental factors that influence adsorption of organic compounds in soil is the temperature. 7,11 It is often assumed that adsorption is an exothermic process, whereby an increase in temperature leads to decreased adsorption and increased desorption rates. 12,13 However, thermodynamic studies have shown a highly variable relationship to temperature due to the complexicity of the soil environment.…”