Crystal Structure and Enzymology of Solanum tuberosum Inositol Tris/Tetrakisphosphate Kinase 1 (StITPK1)
Hayley L. Whitfield,
Raquel Faba Rodriguez,
Megan L. Shipton
et al.
Abstract:Inositol phosphates and their pyrophosphorylated derivatives
are
responsive to the phosphate supply and are agents of phosphate homeostasis
and other aspects of physiology. It seems likely that the enzymes
that interconvert these signals work against the prevailing milieu
of mixed populations of competing substrates and products. The synthesis
of inositol pyrophosphates is mediated in plants by two classes of
ATP-grasp fold kinase: PPIP5 kinases, known as VIH, and members of
the inositol tris/tetrakisphosphate… Show more
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