Crystal structure and catalytic activity of a copper(II) complex based on a tetradentate bis-benzimidazole diamide ligand

Potent inhibition of protein tyrosine phosphatases by copper complexes with multi-benzimidazole derivatives

“…In addition, the bands are slightly blue shift and the energy enhanced with the ligand and ligand to metal charge transfer band (LMCT). A board much less intense d-d band in d 9 electron configuration is observed in the range of 600-800 nm, also indicating copper complexes exist in the solution (Mohapatra et al 2008;Bharti et al 2002).…”

A Novel Dinucleating Ligand-Containing Hexabenzimidazoles and Its Dinuclear Zinc Complex Bridged by a Carboxylate Group for the Hydrolysis of 2-Hydroxypropyl-p-nitrophenyl phosphate

“…Recently, many synthetic mononuclear and dinuclear zinc(II) complexes [28][29][30][31][32] of ligands incorporating benzimidazoles have drawn much attention, because they are useful to elucidate the nature of the active site of the hydrolytic enzyme [28][29][30][31][32][33][34][35] and the catalytic mechanism.…”

Synthesis and spectral studies of copper complexes using a N-octylated bis benzimidazole diamide ligand

“…N,N -bis(benzimidazolyl-2yl)(methyl)pentane diamide (GBGA). This ligand was synthesized using a procedure reported earlier [13]. The product was characterized by 1 H NMR spectra.…”

“…1 . N-octylation of GBGA to prepare O-GBGA was carried out as earlier [13]. GBGA (500 mg) was suspended in 20 ml of dry DMF and was stirred with dry K 2 CO 3 (350 mg) for 4-5 h on a water bath at a temperature of 70-75 • C. Octyl bromide (0.44 ml) was added to the turbid solution and was allowed to stir for next 72 h on a water bath at a temperature of 70-75 • C. Subsequently the solvent was stripped off on a rotary evaporator and the residue was extracted with chloroform.…”

“…This was filtered and dried on anhydrous CaCl 2 . This was recrystalized with hot methanol and analyzed for the composition (C 37 We have earlier reported single crystal structures for a number of Cu(II) complexes with similar bis-benzimidazole diamide ligands that show clear evidence of the binding of this class of ligands through the amide carbonyl rather than amide NH [11][12][13][14]. Further in the synthetic procedure no base was employed so as to deprotonate the amide NH as has been reported for amides that bind through amide NH rather than amide carbonyl [15].…”