Crystal-Storing Histiocytosis in a Patient with Nodal Marginal Zone Lymphoma

Abstract

We present a case of a 72-year-old male diagnosed with concurrent crystal-storing histiocytosis and nodal marginal zone lymphoma with plasmacytic differentiation following a finding of new axillary lymphadenopathy during active surveillance for an early stage lung cancer. A panel of ancillary studies was performed to help establish the diagnosis and to exclude other histologic mimics. We share this case to promote awareness of this rare entity, discuss its association with immunoglobulin-producing lymphomas and review an approach to cases with CSH to avoid misdiagnosis".