Crystal engineering of molecules with through-space α-effect hydrogen bonds: 3a,6 : 7,9a-diepoxybenzo[de]isoquinolines possessing a free amino group

Abstract

This manuscript reports the synthesis, X-ray characterization and DFT study of a series of all-cis 3a,6:4,5:7,9a-triepoxy and 3a,6:7,9a-diepoxybenzo[de]isoquinolines obtained by the tandem intramolecular [4+2] / [4+2] cycloaddition in bis-furans (the...