Cryptosporidium and cryptosporidiosis: The Asian perspective

Cryptosporidium parvum in Children with Diarrhea in Zahedan, Iran

“…Cryptosporidium was identified in 4 out of 707 school children from Turkey (0.6%); all the isolates belonged to the C. parvum bovine genotype (34). The current results are consistent with the reports from Saudi Arabia, Iran, Kuwait, and Turkey (8,(22)(23)(24)(25)(26)(27)(28)(29)(30)(31)(32)(33)(34)(35)(36).…”

“…In immunocompromised patients, it may also cause a prolonged severe disease. This coccidium is a major opportunistic pathogen in AIDS patients (2)(3)(4)(5)(6)(7)(8)(9)(10)(11)(12). Cryptosporidium oocysts in fecal samples are characterized via microscopic examination after concentrating using different methods, including flotation and formol-ether concentration techniques.…”

Case Report: Diagnosis of Cryptosporidiosis in Renal Transplantation in a Low-Prevalence Setting

“…This appears consistent with published data suggesting a low prevalence for cryptosporidiosis in this region. 2,3 The higher positivity rate for Cryptosporidium microscopy over the GIP is likely a result of a higher pretest probability when clinicians request specifically for the specialized mAFB microscopy test.…”

“…The disease incidence varies from 0.34% to 28.5%, reflecting environmental pathogen burden. 2,7 In a retrospective, single-center study in India, Bhadauria et al 8 reported that 119/1,235 (28.5%) renal transplant recipients required hospitalization and evaluation for diarrheal illness. Of these, 34/119 (28.5%) patients had cryptosporidiosis diagnosed through mAFB staining of stool samples.…”

“…is ubiquitously distributed in the environment, although prevalence of the disease is much more common in developing countries than in developed countries. 1,2 Although the disease is largely self-limiting in the immuncompetent host, treatment in the immunocompromised population such as in the organ transplant recipients is particularly challenging, because of its propensity to cause significant morbidity and a lack of antiparasitic therapeutic options. Diagnosis of the disease in the susceptible population is dependent on having a low index of suspicion, especially in a low-prevalence setting, because routine stool sampling for ova, cysts, and parasites is not diagnostic.…”