These days it is difficult to imagine a field of activity (private or public) without computer technology. One way or another, the socioeconomic activity of an individual or society is performed with the help of ICT, Internet, computer technology and software products. For example, in the social sphere, these days it is difficult to imagine the functioning of the educational environment at various levels without ICT, both on the part of the teacher and the student perform many functions on the Internet. In the economic sphere, for example, the financial market, the circulation of financial resources, it is not new to anyone that elementary transactions (payment of utility bills, transfer of monetary resources between subscribers, etc.) can be implemented using a mobile phone or tablet. However, questions of a fundamental nature are not sufficiently considered, what is the current situation with the network resources of regional socioeconomic systems. In our understanding, the socioeconomic system is considered as an object (subject) that constantly interacts with the external environment, offers to exchange its resources (monetary or productive), such systems have boundaries within their motives and needs for interaction with the external environment. By the external environment we mean the regional territory (region) in which the socioeconomic system is undertaken to realize its interests. In the materials of the publication by the author: a general approach to understanding the foundations of organizational and economic network resources of regional socioeconomic systems is proposed; the fundamental constituent elements of regional socioeconomic systems (economic socioeconomic systems of the region (extra-regional and intra-regional), network interactions between socioeconomic systems, the mechanism of state regulation of regional network interactions, the institutional environment in the region) are proposed; adapted to the subject of the study "Readiness Index for the Network Economy" proposed by the World Economic Forum; presented in the author's understanding of the economic efficiency of network resources of regional socioeconomic systems.